Alpha-tocopherol and alpha-tocopheryl quinone levels in cervical intraepithelial neoplasia and cervical cancer.
This cross-sectional study from the Albert Einstein College of Medicine in New York City, USA, examined the relationship between vitamin E blood levels in women and the incidence of cervical cancer and its precursor (cervical intraepithelial neoplasia). The surveyed group consisted of 72 women, 37 of whom had the said precursor and 14 of whom had been diagnosed with cervical cancer. The control group consisted of 21 healthy women. The results showed that the concentrations of the antioxidant vitamin E were significantly lower in the blood plasma of the affected women in comparison to the control group. This confirms earlier studies showing that low levels of antioxidant micronutrients in the blood - and the resulting lack of protection against aggressive "free radicals" - may be frequently found in patients with cervical intraepithelial neoplasia. Further details can be found in the study.
Palan PR, Woodall AL, Anderson PS, Mikhail MS. Alpha-tocopherol and alpha-tocopheryl quinone levels in cervical intraepithelial neoplasia and cervical cancer. Am J Obstet Gynecol. 2004 May;190(5):1407-10.