Anti-diabetic potential of resveratrol

Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic beta-cell dysfunction in streptozotocin-nicotinamide-induced diabetic rats.

This study investigated the effects of resveratrol in regulating hyperglycemia (high blood sugar levels), pro-inflammatory factors, insulin secretion and antioxidant defenses in diabetes. Oral resveratrol was administered (5 mg/kg body weight) to diabetic rats for 30 days. The results of the present investigation demonstrated that resveratrol exhibited significant anti-diabetic effects by attenuating hyperglycemia, enhancing insulin secretion and antioxidant defense in diabetic rats. Further details can be found in the study.
Palsamy P, Subramanian S. Ameliorative potential of resveratrol on proinflammatory cytokines, hyperglycemia mediated oxidative stress, and pancreatic beta-cell dysfunction in streptozotocin-nicotinamide-induced diabetic rats. J Cell Physiol. 2010 Aug;224(2):423-32.


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