Arachidonic acid diet attenuates brain Aβ deposition in Tg2576 mice.
Because of its ability to form brain plaques, the amyloid β-protein is believed to play a key role in the development of Alzheimer's disease. This study evaluated the effects of arachidonic acid, an omega-6 fatty acid, on the deposition of amyloid β-proteins in the brain. For 9 months, mice were treated with a diet containing arachidonic acid. The results showed that the treatment with arachidonic acid prevented amyloid β-protein deposition in the brain. Further details can be found in the study.
Hosono T, Nishitsuji K, Nakamura T, Jung CG, Kontani M, Tokuda H, Kawashima H, Kiso Y, Suzuki T, Michikawa M. Arachidonic acid diet attenuates brain Aβ deposition in Tg2576 mice. Brain Res. 2015 Jul 10;1613:92-9.