Ascorbate effect on cytokine stimulation of HIV production.
Tumor necrosis factor alpha (TNF-alpha) is a pro-inflammatory factor whose levels are elevated in patients with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS). This study evaluated the effect of vitamin C (ascorbic acid) on virus activation following treatment with inflammatory factors. The experiments were performed with cells. The results showed that vitamin C reduced virus activation. Further details can be found in the study.
Harakeh S, Jariwalla RJ. Ascorbate effect on cytokine stimulation of HIV production. Nutrition. 1995 Sep-Oct;11(5 Suppl):684-7.