Mechanism of action of Coenzyme Q10 in essential hypertension
Ten patients with hypertension were treated with oral coenzyme Q10 for 10 weeks. At the end of this pilot study their blood pressure decreased. Systolic blood pressure decreased from 161.5 mmHg to 142.2 mmHg. Diastolic pressure decreased from 98.5 mmHg to 83.1 mmHg. In addition, their cholesterol levels had also decreased. These results showed that coenzyme Q10 is effective in lowering high blood pressure in hypertensive patients and that additional benefits could be observed. Further details can be found in the study.
The force with which blood is pressed against blood vessel walls represents the measurable blood pressure. The level of our blood pressure is directly dependent on various factors, in particular on the pumping force of the heart, the blood volume, and the elasticity of the blood vessels. Hypertension is a chronic medical condition in which the blood pressure in the arteries is persistently elevated. It can be caused by a too strong pumping function of the heart – which generally leads to an increased upper (systolic) blood pressure value. More frequently, the lower (diastolic) blood pressure value is elevated, a condition that is generally caused by a “spasm” (contraction) of the (smooth) muscle cells of the artery walls, causing the narrowing of the blood vessel diameter and the rise of the (diastolic) pressure. The most frequent cause of this artery spasm is a chronic deficiency of micronutrients in billions of artery wall cells. If high blood pressure conditions persist for a long time, they can lead to damage in other organs, including strokes, coronary heart disease, failure of the kidneys, eyes and other organs.
V Digiesi, F Cantini, G Bisi, GC Guarino, A. Oradei, GP Littarru. Mechanism of action of Coenzyme Q10 in essential hypertension. January 1992