EGCG and Polyphenon E Attenuate Inflammation-Related Mouse Colon Carcinogenesis Induced by AOM Plus DDS
This study investigated whether epigallocatechin gallate (EGCG) and Polyphenon E (Poly E), a mixture of green tea catechins, suppress inflammation-related colon cancer. Colonic tumors were induced in male mice aged 5 weeks. The animals received drinking water containing EGCG or Poly E for 17 weeks. The results provided evidence that the tested micronutrient combination supported the suppression of cancer development in the inflamed colon. Further details can be found in the study.
Y Shirakami, M Shimizu, H Tsurumi, Y Hara, T Tanaka, H Moriwaki. EGCG and Polyphenon E attenuate inflammation-related mouse colon carcinogenesis induced by AOM plus DDS. Molecular Medicine Reports. May 1, 2008 Pages: 355-361.