Liver Disease


Worldwide, millions of people suffer from liver disease. Its main cause is one or the combination of the following factors, such as inflammation, drug treatments, alcohol consumption, overweight, obesity and infections.

Inflammation of the liver is called hepatitis and the most common causes are liver toxicity, infections and certain diseases.

Liver toxicity is common, especially with drug treatments. Many people use painkillers and fever-reducing medicine without being aware of their likelihood for causing serious, sometimes deadly, consequences when taken in excess. Easy access and an abundant presence make these drugs the most common culprit for accidental and potentially life-threatening overdose. Accidental poisoning can lead to liver failure requiring liver transplants. The toxicity of drugs depletes the body’s antioxidant pool. Such depletion exposes the body to free radical damage, thus increasing the risk of many other adverse effects.

However, scientific discoveries that cast new light on the role of nutrients in treating liver toxicity have been made. The results indicate that vitamin C, amino acids and other natural compounds can be effective in treating such condition.


Hepatitis can progress to fibrosis (scarring of the liver) and to conditions associated with high mortality such as cirrhosis and liver cancer.

Cirrhosis is the result of exacerbate fibrosis that changes the normal structure of the liver. In its final stages cirrhosis is usually irreversible and a liver transplant may be necessary. Cirrhosis increases the risk of developing liver cancer.

Liver cancer incidence has dramatically increased worldwide. Invasion, metastasis and recurrence contribute to the high mortality rate of this disease. Interestingly, it was shown that micronutrients such as lysine, proline and ascorbic acid, together with epigallocatechin gallate or green tea extract, synergistically exert anti-cancer activity. The scientific literature also highlights the pivotal role of other micronutrients in fighting liver cancer, such as N-acetylcysteine, selenium, copper and zinc.


This section of the Library documents research and clinical studies that show the effectiveness of vitamins and other micronutrients against liver disease.

Scientific Studies

April 26, 2016

Micronutrient supplementations decrease health risks associated with hepatitis

April 26, 2016

Liver diseases are associated with low levels of vitamin D

April 26, 2016

Vitamin D deficiency is common in patients with liver disease

April 26, 2016

Natural compounds are effective against liver disease

April 26, 2016

Antioxidants protect against cadmium toxicity

April 26, 2016

Carnitine supports liver regeneration

April 26, 2016

Tea compounds protect against hepatitis

April 26, 2016

Hepatitis A reduces body defenses against oxidative stress

April 26, 2016

Selenium and zinc protect against oxidative stress

April 26, 2016

Glutamine and vitamin E protect against liver damage

April 26, 2016

Vitamin supplementation helps to fight liver disease

April 26, 2016

Vitamin D supplementation is effective in patients with liver disease

April 26, 2016

Liver diseases reduce blood levels of vitamins

April 26, 2016

Low zinc concentrations are associated with cirrhosis

April 26, 2016

Glutamine enhances the antioxidant defenses

April 26, 2016

Zinc deficiency is associated with liver disease

April 26, 2016

Green tea extract is effective against liver fibrosis

April 26, 2016

Green tea compound EGCG suppresses liver inflammation

April 26, 2016

Green tea extract inhibits liver fibrosis

April 26, 2016

Zinc reduces inflammation in patients with liver disease

April 26, 2016

Vitamins C and E support antioxidant defenses of the liver

April 26, 2016

A green tea compound prevents liver toxicity

April 26, 2016

Micronutrient supplementation prevents liver injury

April 26, 2016

The beneficial effects of supplemented oils on liver diseases

April 26, 2016

Liver cancer patients benefit from B vitamin supplementation

April 26, 2016

Vitamin C supplementation protects against liver disease

April 26, 2016

Betaine protects the liver

April 26, 2016

The protective effects of betaine against liver diseases

April 26, 2016

Micronutrients protect against liver damage