Oral Magnesium Supplementation Decreases C-reactive Protein Levels in Subjects with Prediabetes and Hypomagnesemia: A Clinical Randomized Double-blind Placebo-controlled Trial.
C-reactive protein is a marker for inflammation and higher concentrations are associated with an increased risk for diabetes. This study determined whether magnesium supplementation modifies C-reactive protein (hsCRP) levels in healthy adults with prediabetes (high blood sugar levels but not in the diabetes range) and low magnesium levels (hypomagnesemia). A total of 62 men and non-pregnant women aged 18-65 years, with diagnosis of prediabetes and hypomagnesemia, were enrolled. The researchers found that magnesium supplementation decreased hsCRP levels in healthy participants with prediabetes and hypomagnesemia, thus indicating a diabetes-preventive effect of this micronutrient. Further details can be found in the study.
Simental-Mendía LE, Rodríguez-Morán M, Guerrero-Romero F. Oral magnesium supplementation decreases C-reactive protein levels in subjects with prediabetes and hypomagnesemia: a clinical randomized double-blind placebo-controlled trial. Arch Med Res. 2014 May;45(4):325-30.