Maternal prenatal use of vitamins and folic acid reduces the risk of leukemia in offspring

Maternal supplementation with folic acid and other vitamins and risk of leukemia in offspring: a Childhood Leukemia International Consortium study.

This study analyzed the effect of maternal prenatal vitamin supplementation with folic acid and other vitamins on childhood leukemia. Data on prenatal use of folic acid and vitamins were obtained from 12 studies, including more than 7,000 children with leukemia and 11,635 without leukemia. The results suggested that maternal prenatal use of vitamins and folic acid reduces the risk of leukemia in offspring. More details can be found in the study.
Metayer C, Milne E, Dockerty JD, Clavel J, Pombo-de-Oliveira MS, Wesseling C, Spector LG, Schüz J, Petridou E, Ezzat S, Armstrong BK, Rudant J, Koifman S, Kaatsch P, Moschovi M, Rashed WM, Selvin S, McCauley K, Hung RJ, Kang AY, Infante-Rivard C. Maternal supplementation with folic acid and other vitamins and risk of leukemia in offspring: a Childhood Leukemia International Consortium study. Epidemiology. 2014 Nov;25(6):811-22.


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