Soy-derived compounds protect the lungs against adverse effects of radiation therapy

Radioprotection of lung tissue by soy isoflavones.

This study evaluated the role of soy-derived compounds, isoflavones, in the protection of lungs during radiation therapy. The experiments were performed with mice which were treated with soy isoflavones for 3 days before and up to 4 months after radiation. It was found that soy isoflavones protected the lungs against adverse effects of radiation including skin injury, hair loss, inflammation, and others. These results provide evidence for a protective effect of soy against radiation therapy. Further details can be found in the study.
Hillman GG, Singh-Gupta V, Lonardo F, Hoogstra DJ, Abernathy LM, Yunker CK, Rothstein SE, Rakowski J, Sarkar FH, Gadgeel S, Konski AA, Joiner MC. Radioprotection of lung tissue by soy isoflavones. J Thorac Oncol. 2013 Nov;8(11):1356-64.


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