Resveratrol ameliorates diabetes-induced kidney disease

Resveratrol ameliorates early diabetic nephropathy associated with suppression of augmented TGF-β/smad and ERK1/2 signaling in streptozotocin-induced diabetic rats.

This study examined the beneficial effects of resveratrol on diabetes-induced kidney disease (diabetic nephropathy). Diabetic rats were treated with or without resveratrol at 0.75mg/kg body weight 3 times a day for 8 weeks. The results revealed that resveratrol ameliorates changes associated with early diabetic nephropathy. Further details can be found in the study.
Chen KH, Hung CC, Hsu HH, Jing YH, Yang CW, Chen JK. Resveratrol ameliorates early diabetic nephropathy associated with suppression of augmented TGF-β/smad and ERK1/2 signaling in streptozotocin-induced diabetic rats. Chem Biol Interact. 2011 Mar 15;190(1):45-53.


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