Low magnesium levels are associated with an increased risk of stroke

Serum Magnesium and the Risk of Ischemic Stroke among Women

This research was performed to analyze the association between magnesium levels and the risk of stroke among women. 460 patients were analyzed and compared to healthy controls. The results suggested that low magnesium blood levels (<2.0 mg/dL) are associated with an increased risk of stroke among women. Further details can be found in the study.
As in coronary artery disease, the underlying disease process for cerebrovascular disease –the narrowing of the arteries that supply blood to the brain – is arteriosclerosis. Here too, the process starts with a weakening of the blood vessel walls, most frequently caused by an insufficient dietary intake of vitamins and other micronutrients. This leads to an underproduction of collagen and other reinforcement molecules in the artery walls and to the initiation of a repair process to compensate for the growing instability of these walls. The arteriosclerotic plaques that – with time – narrow the blood flow in the neck (carotid) arteries or brain (cerebral) arteries is essentially an overshooting repair process for the vitamin-deficient artery wall. A stroke occurs when the already narrowed arteries are clogged and the supply of oxygen and nutrients to billions of brain cells is interrupted, causing permanent damage.
Sally N Akarolo-Anthony, Monik C Jimenez, Stephanie E Chivue, Walter C Willett, Kathryn M Rexrode. Serum Magnesium and the Risk of Ischemic Stroke among Women. Circulation 2013; 127: AP402


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