Zinc decreases inflammatory response

Zinc supplementation decreases oxidative stress, incidence of infection, and generation of inflammatory cytokines in sickle cell disease patients.

This study evaluated the effects of zinc supplementation on inflammation in sickle-cell disease (SCD), a disorder of red blood cells. 36 SCD patients were given either 25 mg zinc three times a day for 3 months or a placebo. Zinc-supplemented patients showed a significant decrease in inflammation. These results suggested that zinc supplementation reduced the inflammatory status in SCD patients. More details can be found in the study.
Bao B, Prasad AS, Beck FW, Snell D, Suneja A, Sarkar FH, Doshi N, Fitzgerald JT, Swerdlow P. Zinc supplementation decreases oxidative stress, incidence of infection, and generation of inflammatory cytokines in sickle cell disease patients. Transl Res. 2008 Aug;152(2):67-80.


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