Zinc supplementation helps malnourished children with infections of the intestines

Summary This study, conducted by a Bengali and an American research institute, investigated the effects of zinc supplementation in malnourished children with shigellosis (infection of the intestines caused by Shigella bacteria). The study was conducted in a Bengali hospital and included 56 moderately malnourished children between 12 and 59 months. The children received liquid zinc or a…

Zinc supplementation in children with cholera

Summary A study conducted by Bengali researchers investigated the impact of zinc supplementation in children with cholera. The study involved 179 children with diarrhea and positively tested on cholera microbes. 90 patients received a daily zinc supplementation combined with the conventional therapy (antibiotics); 89 patients received a placebo in addition to the conventional treatment. Among…

Vitamin D deficiency in COVID-19 patients

Summary This study by several Iranian research institutes investigated the connection between vitamin D levels and the severity of COVID-19 infections. 123 people participated in this study, including 63 COVID-19 patients and 60 healthy participants. The study showed that COVID-19 patients had significantly lower vitamin D levels and a significantly higher number of ACE receptors,…

The essential role of vitamin C and zinc in child health

Summary According to a Swiss study, micronutrient deficiency is a limiting factor in children’s health. Studies from several countries show that vitamin C and zinc deficiencies are increasing. Optimal micronutrient levels are essential for a well-functioning immune system and to combat infections. Deficiencies can induce an impaired immune defense. Vitamin C and zinc, for example,…

Zinc supplementation beneficial in children suffering from infections

Summary Zinc deficiency is widely recognized as a risk factor for morbidity and mortality, especially among young children. Acute and persistent diarrhea, a common cause of death in young children, can be induced by zinc deficiencies. Supplementation of zinc can be beneficial to reduce the duration of acute and persistent diarrhea. More details can be…

Zinc helps against infection and inflammation

Summary Zinc is a micronutrient essential in maintaining a well-functioning immune system. Its deficiency can induce dysfunctions of the immune system and make people more susceptible to infectious diseases. Inflammations are also related to zinc deficiency since zinc has an important influence on pro-inflammatory factors in the human body. In addition to an adequate diet,…

Vitamin C improves immune cell function

Summary Immune cells require large amounts of vitamin C to function well. An increased turnover of vitamin C in the body due to, for instance, stress and illness can induce vitamin C deficiency when its intake is too low. Several immune processes are influenced by vitamin C. Consequently, a sufficient level of vitamin C is…

Omega-3 fatty acids reduce inflammatory processes

Summary According to several studies, omega-3 fatty acids have beneficial effects on inflammatory processes in the whole body. This is because omega-3 fatty acids inhibit several factors inducing inflammations. Animal studies have shown that omega-3 fatty acids are beneficial in treating inflammatory diseases like Inflammatory Bowel Disease, Rheumatoid Arthritis, and asthma. More details can be…

The therapeutic effects of curcumin

Summary Curcumin has shown significant regulating effects on immune cells and, thereby, beneficial effects in modulating the immune system, which is involved in inflammations and other chronic diseases. There is a lower incidence of chronic diseases in people from countries where curcumin is consumed. This is due to its antioxidant and anti-inflammatory effects. Studies have…

The beneficial effect of curcumin on inflammation

Summary An increasing number of scientific studies show that natural supplements significantly improve immune function. Supplements have gained importance due to their minimal side effects, low costs, and abundance. More than 7000 articles reported about the various positive aspects of curcumin, including, among others, its antioxidant and anti-inflammatory effects. Therefore, curcumin could be a therapeutic…

Curcumin can help in the prevention and treatment of several common diseases

Summary According to several studies, curcumin could be beneficial in the prevention and treatment of common diseases, including infectious diseases. Curcumin has, among others, anti-inflammatory, immunomodulatory and anti-microbial effects, making it an effective substance to inhibit related diseases. Additionally, curcumin is inexpensive, does not have any adverse side effects, and could also be a beneficial…

Quercetin supplementation helps fight inflammation

Summary Quercetin is known for its antioxidative and anti-inflammatory effects. An Iranian study investigated the effects of quercetin supplementation on inflammation and oxidative stress in amateur athletes. 60 participants were involved, which were divided into 4 subgroups of each 15 participants. In the course of 8 weeks, one subgroup received quercetin and vitamin C, one…

Vitamin D prevents respiratory infections in patients with Inflammatory Bowel Disease

Summary In this study, researchers aimed to investigate the (preventive) effect of vitamin D supplementation on the incidence of seasonal flu and respiratory tract infections in patients with Inflammatory Bowel Disease (IBD) during the winter and early spring. 223 patients with IBD were included and categorized in two groups: One test group received a vitamin…

Vitamin D deficiency increases COVID-19 risk

Summary A study conducted by the University of Chicago examined the association between vitamin D levels and other clinical characteristics related to COVID-19. 489 patients were involved. Patients with a deficient vitamin D level showed a 1.77 times greater risk to test positive for COVID-19. This study showed a direct association between vitamin D deficiency…

Vitamin D improves mortality rate in COVID-19 patients

Summary This study, conducted by Turkish researchers, investigated the effect of vitamin D levels on COVID-19 severity and mortality in 149 COVID-19 patients. Results showed that patients with critical complaints had significantly lower vitamin D levels than patients with moderate COVID-19 complaints. Vitamin D insufficiency was measured in 93.1% of the patients with critical complaints.…

Vitamin D reduces negative consequences in COVID-19 patients

Summary This study, conducted by several Iranian and American research institutes, investigated the association between vitamin D levels and its effect on several adverse clinical outcomes and parameters related to immune function and mortality rate in 235 COVID-19 patients. This study showed a significant association between vitamin D sufficiency, less severe clinical complaints, and better…

Micronutrient combination can lower LDL cholesterol

Summary This clinical cross-over study from Italy investigated the lipid-lowering effect of monacolin K, L-arginine, coenzyme Q10, and ascorbic acid. The study involved 20 patients with high cholesterol levels who supplemented their diet with the micronutrients mentioned above for 8 weeks. Subsequently, total cholesterol, low-density lipoprotein cholesterol (LDL) and high-density lipoprotein cholesterol (HDL), triglycerides, fasting…

Folic acid can reduce stroke risk in patients with cardiovascular disease

Summary A meta-analysis was used to examine the effect of folic acid supplementation in patients with cardiovascular diseases. A total of 12 randomized controlled trials with 47,523 participants were evaluated. The researchers found that supplementation led to a significantly reduced risk of stroke in patients with cardiovascular disease. Further details can be found in the…

Coenzyme Q10 can lower lipid levels in patients with coronary heart disease

Summary A systematic review and meta-analysis were used to investigate the effect of dietary supplementation with coenzyme Q10 on the lipid profile of patients with coronary heart disease. The lipid profile is considered an important indicator for the development of heart disease. 8 studies were included, with 267 participants in intervention groups and 259 in…

Dietary intake of vitamins can reduce risk of cardiovascular disease

Summary This study investigated the effects of an increased dietary intake of vitamin C, carotenoids, and α-tocopherol (vitamin E) on the risk of cardiovascular disease. For this purpose, 69 prospective studies were analyzed that included participants who adjusted their diet according to an increased vitamin intake. The result showed that the intake of vitamin C,…

Coenzyme Q10 improves muscle complaints under statin therapy

Summary Cholesterol-lowering drugs, so-called statins, are intended to prevent heart attacks or strokes in people with coronary heart disease. However, they are associated with several side effects. This meta-analysis evaluated the effect of dietary supplementation with coenzyme Q10 on statin-induced muscle damage. The analysis of 12 studies with 575 patients showed that coenzyme Q10 can…

Supplements containing antioxidant micronutrients and glutamine improve wound healing

Summary A study conducted by several German researchers investigated 20 trauma patients with disorders in wound healing. For 14 days, these patients received a supplement containing antioxidant micronutrients. The level of micronutrients and other parameters were measured before and after the supplementation period. Additionally, the period of wound closure was measured. The results showed that…

Vitamin C supplementation positively affects common cold-induced asthma

Summary This study is an overview of three trials investigating the effect of vitamin C supplementation on cold-induced asthma attacks. In total, 79 people participated. All three studies found beneficial effects of vitamin C supplementation against asthma attacks and other asthma symptoms. According to these studies, the administration of vitamin C alleviates common cold symptoms…

Vitamin C reduces cold incidence in men with low vitamin C level

Summary Early signs of vitamin C deficiency often go unrecognized and may manifest as a reduced desire to be physically active. Moreover, it is often associated with increased cold duration and severity. A study conducted by several American institutes investigated the effects of vitamin C supplementation on physical activity and respiratory tract infections during the…

Vitamin D supplementation prevents acute respiratory tract infections

Summary This study is an overview of several studies on the preventive effects of vitamin D supplementation on acute respiratory tract infections. 25 eligible studies were identified based on individual participant data. These studies showed a reduced risk of acute respiratory tract infections and a preventive and protective effect in all participants after daily or…

B vitamins improve risk factors for cardiovascular disease

Summary In this study from China, subjects with stable coronary heart disease were evaluated for a positive change in their inflammation levels and blood lipids following vitamin B supplementation. After 12 weeks, concentrations of triglycerides, total cholesterol, and HDL levels were significantly improved. A change in homocysteine blood levels, considered a risk factor for numerous…

Coenzyme Q10 lowers cholesterol levels in patients with coronary heart disease

Summary A meta-analysis examined eight studies that included 267 participants in intervention groups and 259 subjects in placebo groups. The analysis results showed that taking coenzyme Q10 significantly lowered total cholesterol levels and increased HDL (“good cholesterol”) cholesterol levels in participants with coronary heart disease. Please see the study for more information. References Mohammad Vahid…

Combination of vitamin C, thiamine, and hydrocortisone beneficial for the treatment of sepsis and septic shock after cardiac surgery

Summary A combination of vitamin C, thiamine (vitamin B1), and hydrocortisone was investigated in 24 patients with septic shock after cardiac surgery. The participants were divided into two groups: group 1 received a placebo, and group 2 received a combination of the mentioned micronutrients. After 4 days, the required vasopressor dose (medication that tends to…

Combination of vitamin C, thiamine, and hydrocortisone beneficial for patients with severe pneumonia

Summary In this study, the effects of a combination of vitamin C, thiamine (vitamin B1), and hydrocortisone were investigated in a treatment group of 53 patients with severe pneumonia. These patients were compared to a control group of 46 patients who did not receive this micronutrient combination. The results showed that the mortality rate decreased…

Vitamin C may reduce the duration of mechanical ventilation in critically ill patients

Summary This meta-analysis included 8 trials with 685 patients in total. Results showed that vitamin C decreased the length of mechanical ventilation on average by 14%. Vitamin C showed beneficial effects, particularly in patients with the longest ventilation (most severe diseased patients). In 5 trials, including 471 patients requiring ventilation for over 10 hours, ventilation…