Summary This study investigated the effect of high-dose intravenous vitamin C supplementation in patients receiving intensive care treatment for Covid-19. 54 critically ill patients were involved in this study, including 26 patients who received the vitamin C infusion and 28 patients who received a placebo infusion. According to this study, vitamin C supplementation is an…
Summary This study investigated the effect of high-dose zinc infusions on Covid-19 patients. 33 hospitalized adults participated in this study, including 15 patients who received a high-dose zinc infusion and 18 patients who received a placebo. Participants with zinc infusion showed an improved zinc level after the administration period, without adverse side effects. More details…
Summary 986 hospitalized patients with Covid-19 were involved in this study, including 151 patients (16%) who received vitamin D therapy. This study showed that supplementation of vitamin D reduced the risk of mortality in Covid-19 patients. More details can be found in the study. References Stephanie F Ling, Eleanor Broad, Rebecca Murphy, Joseph M Pappachan,…
Summary This study investigated the effect of vitamin D3 supplementation in Covid-19 patients. 66 residents of a nursing home participated in the study. The patients received the vitamin D3 supplementation during or in the month before the Covid-19 infection (intervention group). It was shown that vitamin D3 intake was associated with less severe Covid-19 and…
Summary This study investigated the effects of vitamin D on inflammatory factors in COVID-19 patients. One group of patients received vitamin D daily; the other group only received the standard treatment. The results showed that vitamin D supplementation has a beneficial effect on COVID-19 by reducing inflammatory factors. No side effects were observed. More details…
Summary A double-blind, placebo-controlled study conducted by the University of Nashville investigated the relationship between a dietary supplement containing green tea extract and its effect on cholesterol levels. 240 men and women over 18 years of age with low to moderate increases in blood cholesterol (hypercholesterolemia) were examined over a period of 3 months. Study…
Summary In another large randomized, placebo-controlled clinical trial, which involved several American universities, the influence of green tea extracts (catechins) was investigated. The study participants were all postmenopausal women, with 936 of them completing the one-year trial. Compared to the control group, catechin supplementation was associated with a significant reduction in total and LDL cholesterol…
Summary A randomized, double-blind, placebo-controlled trial investigated the effect of two B vitamins (folic acid and vitamin B6) on the metabolism of patients with coronary heart disease. After three months of vitamin B supplementation, the three most important risk factors of fat metabolism showed a significant improvement. Blood levels of triglycerides and total cholesterol were…
Summary As early as 1992, the USDA Human Nutrition Research Center at Tufts University in Boston published a randomized field study involving several hundreds of participants of all age groups. The results of the study showed that increased vitamin C blood levels were associated with a reduction in LDL cholesterol (“bad cholesterol”) and an increase…
Summary Diabetes is a known risk factor during pregnancy, when the disease can lead to serious complications as a result of metabolic disorder. A randomized, controlled study at Shanghai University Hospital investigated the effect of vitamin D on the progression of gestational diabetes. Supplementation with high-dose vitamin D significantly improved the insulin needs and other…
Summary A randomized, controlled clinical trial at Cairo University Medical Clinic examined the effect of a dietary supplement containing a combination of B vitamins (B1, B6 and B12) on patients with type 1 diabetes. After only 3 months, this dietary supplement led to a significant decrease in fasting blood glucose levels, long-term blood glucose (HbA1c),…
Summary A randomized clinical trial investigated the effect of vitamin C supplementation on blood glucose control and blood pressure in diabetic patients. After 4 months of vitamin C supplementation, participants showed an improvement in blood sugar levels and a reduction in blood pressure compared to the placebo group. Further details can be found in the…
Summary In another randomized and controlled clinical trial, a joint team of researchers from the University Hospitals of Frankfurt and Hanover examined the effects of vitamin D administration on diabetes progression. The results of this clinical study showed that vitamin D supplementation significantly reduced insulin demands and significantly improved long-term blood glucose levels (HbA1c). No…
Summary 60 patients with type 2 diabetes and low vitamin D levels were enrolled in a placebo-controlled, randomized clinical trial to investigate the effect of vitamin D supplementation on the progression of the disease. Patients who received a vitamin D supplement had a significant reduction in their long-term diabetes score (HbA1c). Blood pressure and blood…
Summary Another randomized double-blind study was conducted as part of an international collaboration between the universities of Copenhagen, Melbourne, Vienna, Warsaw and other hospitals. The study included 420 patients and investigated the influence of coenzyme Q10 supplementation on the progression of chronic heart failure over a period of 2 years. According to the researchers, coenzyme…
Summary In a comprehensive study conducted as part of the Third National Health and Nutrition Examination Survey, 13,131 participants were examined over a period of 12 years. The aim of the study was to find out if low vitamin D blood levels had an effect on the mortality rate of the study participants. The study…
Summary A study carried out by the University of Jerusalem examined the association between vitamin D blood levels and vitamin D supplementation on the mortality rate of patients with heart failure. The study compared 3,009 patients with low vitamin D levels with a control group comprising 46,825 participants . The study showed that vitamin D…
Summary In a randomized clinical trial involving patients suffering from chronic heart failure, the effect of dietary supplements containing a vitamin-mineral combination was investigated. The study was carried out at the Charité Clinic in Berlin and showed that the pumping function of the heart (left ventricular ejection fraction) was significantly improved by the dietary supplement.…
Summary An analysis of 12 clinical trials investigated the correlation between coenzyme Q10 supplementation, a cofactor of cellular energy metabolism, and hypertension. Based on all results, the researchers concluded that coenzyme Q10 supplementation can reduce systolic blood pressure by up to 17 points (mmHg) and diastolic blood pressure by up to 10 points. Among the…
Summary In an evaluation of 11 double-blind, placebo-controlled trials, the correlation between dietary supplementation with the natural amino acid arginine and changes in blood pressure was investigated. The analysis of these trials showed that arginine supplementation led to a highly significant reduction in both systolic and diastolic blood pressure. One particularly remarkable aspect of this…
Summary In a double-blind, placebo-controlled trial with patients suffering from an early form of hypertension (pre-hypertension and stage 1 hypertension), the effect of quercetin on blood pressure was investigated. This dietary supplement led to a reduction in both systolic and diastolic blood pressure. The reduction in diastolic blood pressure was statistically significant (P < 0.01).…
Summary An analysis of 8 clinical trials investigating the association between vitamin C supplementation and essential hypertension showed that vitamin C supplementation led to a significant reduction in blood pressure. For daily supplementation above 500 mg of vitamin C, these results were even statistically significant (P = 0.005). What is particularly remarkable about this research…
Summary A clinical epidemiological study involving more than 2,400 participants in Finland investigated the association between blood levels of vitamin C and the occurrence of stroke. The study participants were patients with hypertension – a condition associated with an increased risk of stroke – who were observed over a period of 10.4 years. The results…
Summary In a clinical study in Stockholm, the association between the use of multivitamin supplements and the occurrence of heart attacks was investigated in almost 3,000 study participants. Participants taking multivitamins had a significantly reduced risk of heart attacks. Further details can be found in the study. References Mary L Fantacone, Malcolm B Lowry, Sandra L Uesugi…
Summary A clinical study among more than 40,000 Japanese people, investigated the association between the intake of green tea, which is rich in natural polyphenols, and the occurrence of cardiovascular disease and cancer. The consumption of large quantities of green tea was associated with a significant reduction in cardiovascular mortality, including a clear reduction in…
Summary A clinical study conducted at the University of Kansas investigated the associations between vitamin D blood levels, vitamin D supplementation and the incidence of cardiovascular disease. Of 10,899 patients observed over a period of 5 years and 8 months, low vitamin D levels were associated with a significantly increased risk of cardiovascular disease and…
Summary In a clinical study coordinated by the Department of Age Research and Preventive Oncology at the German Cancer Research Center in Heidelberg, several thousand study participants were observed over a period of 9.5 years. The study investigated the association between vitamin D deficiency and the most common causes of death. A direct link was…
Summary In a double-blind, placebo-controlled clinical trial involving patients with coronary heart disease, a Norwegian team of doctors showed that micronutrient supplementation with folic acid (vitamin B9) and vitamin B12 had a positive effect on the blood supply to the coronary arteries. During the study period of two years, both basic and maximum blood flow…
Summary A study conducted at the University of California in Los Angeles showed that an increased vitamin intake had a positive effect on the progression of coronary heart disease. This study provided strong evidence because it was documented using coronary angiography. The researchers found an association between supplementary vitamin E intake and an angiographically demonstrated…
Summary A study at the University Hospital of Amsterdam with more than 2,700 participants showed that an increased vitamin C intake was associated with lower blood pressure and other positive parameters. Most importantly, the group of people with the highest vitamin C intake had a one-third lower risk of developing coronary heart disease compared with…
Summary A study involving 11,348 adult Americans aged 25-74 years showed that both overall mortality and mortality from cardiovascular disease were associated with daily vitamin C intake. The subjects with the highest vitamin C intake had a 40% reduced risk of CVD mortality. More details can be found in the study. References Enstrom et al.…
Summary This study focused on the effects of a combination of specific micronutrients, including vitamin C, on COVID-19 infections. It was shown that this micronutrient combination can decrease the expression of ACE2 receptors used by the COVID-19 virus to enter the cells and block the potential interaction of the virus and the ACE2 receptors. According…
Summary In this study, a group of 17 COVID-19 patients received a combination of vitamin D, magnesium, and vitamin B12. 26 COVID-19 patients served as a control group. The patients who received the micronutrients had a lower need for oxygen therapy and intensive care support than patients in the control group. Further details can be…
Summary This study measured the effects of vitamin D supplementation on Intensive Care Unit Admission and death rate among 76 hospitalized COVID-19 patients. The supplementation of a high dose of vitamin D showed that the need for Intensive Care Unit Treatment decreased and reduced the severity of the disease. Further details can be found in…
Summary In this study, vitamin D levels and rates of vitamin D deficiency were measured in 62 patients diagnosed with COVID-19 and 80 healthy controls. The results showed that vitamin D levels were much lower in COVID-19 patients than in the healthy control group. The lowest vitamin D levels were found in the most severe…
Summary This meta-analysis evaluated the results of several studies investigating the effects of vitamin C, including its effect on the length of stay in the ICU. 18 relevant controlled trials were identified with a total of 2004 patients. Vitamin C was found to decrease the length of ICU stay on average by 8%. Further details…
Summary In this study, vitamin and mineral concentrations and several parameters related to immune function were measured in two groups. One group received a vitamin and mineral product daily for 12 weeks; the other group received a placebo. Before and after the intake, vitamin and mineral concentrations and all involved parameters were measured. Among others,…
Summary 40 patients were involved in this study. 20 patients received 100 mg coenzyme Q10 twice a day in combination with a standard sepsis therapy. The other 20 patients received only the standard sepsis therapy. This study showed decreased inflammation markers and a lower death rate in the test group if the micronutrient supplementation was…
Summary This study was conducted in 196 premature infants on alternate days during a period of 28 days. 98 infants received 10000 IU vitamin A, and 98 received a placebo supplement. This study showed that through supplementation of vitamin A the all-cause death rate and oxygen requirements decreased in this vulnerable group of patients. Further…
Summary This study examined whether individuals who regularly use supplements of the antioxidant vitamins E and C have a lower risk of amyotrophic lateral sclerosis (ALS) than nonusers. The study followed 957,740 individuals 30 years of age or older. Regular use of vitamin E supplements was associated with a lower risk of dying of ALS.…
Summary This study examined 5 earlier studies and investigated whether vitamin E intake was associated with amyotrophic lateral sclerosis (ALS). The researchers found that long-term vitamin E supplement use was associated with lower ALS rates and concluded that a possible protective effect of vitamin E in this disease deserves further consideration. Further details can be…
Summary This study reports that a severe vitamin D deficiency in amyotrophic lateral sclerosis (ALS) patients accelerates the rate of decline by 4 times and is associated with a marked shorter life expectancy. The researchers say their findings support a neuroprotective function of vitamin D on motoneurons and propose vitamin D as a reliable prognostic…
Summary This study assessed the safety and tolerability of high doses of coenzyme Q10 (CoQ10) in amyotrophic lateral sclerosis (ALS). CoQ10 may improve the mitochondrial dysfunction in ALS. The researchers found that CoQ10 was safe and well tolerated in 31 patients treated with doses as high as 3,000 mg/day for 8 months. Further details can…
Summary This study investigated the risk of amyotrophic lateral sclerosis (ALS) by analyzing 5 studies involving a total of over 1.1 million participants. The researchers found that consumption of foods high in carotenoids may help prevent or delay onset of ALS. Further details can be found in the study. References Aleksandra Niedzwiecki, Mohd Waheed Roomi, Tatiana Kalinovsky…
Summary This study was based on a food-frequency questionnaire and assessed whether dietary intake of fatty acids, cholesterol, glutamate or antioxidants was associated with the risk of developing amyotrophic lateral sclerosis (ALS). The researchers concluded that a high intake of polyunsaturated fatty acids and vitamin E is associated with a 50-60% decreased risk of developing…
Summary This study assessed the bone health of patients with amyotrophic lateral sclerosis (ALS) and found that the serum concentration of the 25-hydroxyvitamin D form of vitamin D was significantly lower in patients than in controls. Dietary intake of vitamin D was below the recommended level in 10 of the 11 ALS patients studied. Further…
Summary This case report summarizes the case of a 49-year-old male patient suffering from a variant of amyotrophic lateral sclerosis (ALS), who was diagnosed after extensive examinations ruling out other diseases. The patient received treatments that included the restoration of his teeth due to supposed mercury exposure from residual amalgam, as well as supplements such…
Summary This study investigated the relationship between dietary intake of vegetables, fruit, and antioxidants and the risk of amyotrophic lateral sclerosis (ALS). Its findings suggest that higher intake of food rich in antioxidants such as fruit and vegetables confer protection against the development of ALS. Further details can be found in the study. References Sheweita…
Summary This study found statistically significant decreased cerebrospinal fluid and serum levels of copper in amyotrophic lateral sclerosis (ALS) patients compared to the control group. The researchers concluded that their findings indicate an essential trace element imbalance in ALS. Further details can be found in the study. References S A Sheweita, B Y Sheikh Link…
Summary This double-blind trial compared the effects of the methylcobalamin form of vitamin B12 on muscle function in amyotrophic lateral sclerosis (ALS) patients when given intramuscularly in ultrahigh-dose (25 mg/day) and low-dose (0.5 mg/day) for 14 days. The researchers found that ultrahigh-dose intramuscular injection of methylcobalamin may provide a clinically useful measure to improve or…