Lower levels of folate and vitamin B6 increase the risk of atherosclerosis

Summary High levels of the amino acid homocysteine increase the risk of atherosclerosis. This study evaluated the relationship between homocysteine, atherosclerosis and B vitamins. 750 patients with vascular disease were compared with 800 healthy people. Blood levels of homocysteine, folate, vitamin B12 and vitamin B6 were determined. The results showed that lower levels of folate…

Micronutrient supplements support treatment of high blood pressure and diabetes

Summary This research collected studies on the use of dietary supplements in the management of high blood pressure and diabetes. The studies showed that micronutrients were effective and safe substitutes for toxic and expensive conventional drugs. Moreover, it turned out that micronutrients are generally free from side effects. The authors therefore concluded that dietary supplements…

Inadequate micronutrient intake increases risk of high blood pressure

Summary This study analyzed the relationship between the intakes of micronutrients (vitamins and minerals) and developing high blood pressure. Vitamin and mineral intakes were estimated from a three-day food record in 120 children. The researchers found that intakes of vitamin D, calcium and potassium were inadequate, whereas sodium intake was considered to be too high.…

Vitamin C reduces inflammation

Summary The aim of this study was to examine whether vitamin C is capable of reducing inflammation in obese adults with high blood pressure and/or diabetes. 64 patients were given either 500 mg vitamin C twice a day or no treatment. The results showed that vitamin C reduced inflammation in obese patients with high blood…

Vitamin A deficiency in patients with tuberculosis

Summary This study investigated the blood levels of vitamin A in 100 HIV-positive and HIV-negative tuberculosis patients and 144 blood donors. The results showed that vitamin A deficiency is common in tuberculosis and HIV infection, particularly in those patients who are infected with both diseases. It was also found that nutritional supplementation can be beneficial…

Vitamin A deficiency is associated with tuberculosis

Summary In this study the association between vitamin A deficiency and tuberculosis was investigated. 300 participants were categorized as mild tuberculosis and severe tuberculosis. The results showed that severe tuberculosis was associated with vitamin A deficiency. Further details can be found in the study. References T A Pakasi, E Karyadi, Y Wibowo, Y Simanjuntak, N M D Suratih, M Salean, N…

Reduced levels of zinc in pulmonary tuberculosis

Summary This study investigated the blood levels of zinc in tuberculosis patients, with the aim to evaluate the effectiveness of anti-tuberculosis therapy. 50 tuberculosis patients and 30 healthy participants were included and tested for their zinc levels. The authors found that zinc can boost the immune system if applied during the course of treatment, thereby…

Green tea extract protects against tuberculosis

Summary This study analyzed the relationship between oxidative stress (imbalance between the production of free radicals and the antioxidant defenses of the body), tuberculosis and the role of green tea extract in repairing the damage caused by oxidative stress. The experiments were performed with mice. The results showed that there are high levels of oxidative…

Vitamin E reduces the risk of stone formation in tuberculosis patients

Summary This study analysed oxidative stress – the imbalance between the production of free radicals and the body´s ability to counteract their harmful effects through antioxidants – in tuberculosis patients, which is a predisposing factor for renal stone formation. Patients were divided in four groups: healthy people, tuberculosis patients a day before treatment, tuberculosis patients…

Arginine and vitamin D support tuberculosis treatment

Summary This review collected scientific studies on the effects of arginine and vitamin D against tuberculosis. It was shown that arginine and vitamin D can reduce treatment time, reduce infectivity and improve treatment efficacy against drug-resistant tuberculosis. Further details can be found in the study. References Anna P Ralph, Paul M Kelly, Nicholas M Anstey   Link…

Vitamin D accelerates tuberculosis recovery

Summary This study evaluated the effect of vitamin D on tuberculosis, as indicated by “sputum culture conversion”, i.e. an analysis showing that a patient is cured of tuberculosis. 146 patients with tuberculosis were given either vitamin D or no supplementation. The results showed that vitamin D administration hastened recovery from tuberculosis. Further details can be…

Green tea compounds support tuberculosis therapy

Summary This study assessed the effect of green tea catechins in reducing oxidative stress in patients with tuberculosis. Oxidative stress is essentially an imbalance between the production of free radicals and the ability of the body to counteract their harmful effects through neutralization by antioxidants. 200 patients with tuberculosis were enrolled in the study. 100…

Green tea extract inhibits Mycobacterium tubercolosis

Summary This study evaluated the effects of epigallocatechin gallate (EGCG, the main component of green tea) and triclosan (antibacterial agent) against Mycobacterium tuberculosis, the bacterium that causes tuberculosis. The experiments showed that EGCG inhibited Mycobacterium tuberculosis and increased the inhibitory activity of triclosan against this bacterium. More details can be found in the study. References…

Tuberculosis patients have low levels of trace elements

Summary This study evaluated blood levels of trace elements (copper, zinc, selenium and iron) in tuberculosis patients with or without human immunodeficiency virus (HIV). A total of 155 patients with tuberculosis, including 74 patients suffering from HIV, and 31 healthy participants were investigated. The results indicated that tuberculosis patients had reduced levels of trace elements…

Micronutrients improve tuberculosis therapy

Summary Micronutrient deficiency is a key factor in the progression of tuberculosis. Based on this understanding, the present study evaluated the effect of a micronutrient supplementation, including vitamin A, B, C, E and selenium, in adults with tuberculosis. 471 adults infected with human immunodeficiency virus (HIV) and 416 HIV-negative adults with tuberculosis were investigated. The…

Vitamin A and zinc improve tuberculosis treatment

Summary This study investigated whether vitamin A and zinc supplementation increases the efficacy of antituberculosis treatment. 80 patients with tuberculosis were divided into 2 groups: one group received vitamin A and zinc daily for 6 months. The second group received no supplementation. Additionally, both groups were given the standard treatment for tuberculosis. The results showed…

Vitamin C protects against kidney injury

Summary This study investigated the effect of vitamin C on kidney injury as a result of ischemia-reperfusion (restoration of blood flow to body tissues that were blood flow-deficient). The experiments were performed with 32 rats. The results showed that vitamin C had a protective effect against kidney injury. This effect was attributed to the antioxidative…

Green tea compounds protect against kidney damage

Summary FK506 is a drug used to fight rejection after organ transplantation. This study examined the protective effect of green tea compounds (polyphenols) against FK506-induced kidney damage. The experiments were performed with cells. The results showed that tea polyphenols exerted a strong protection against FK506-induced cell death. Further details can be found in the study.…

Vitamin C protects against drug-induced kidney damage

Summary The present study was performed to investigate whether the chronic administration of antioxidant vitamin C provided protection against kidney damage induced by the chemotherapy drug cisplatin. This study was performed with rats. The results suggested that the chronic administration of vitamin C can be beneficial against cisplatin-induced kidney damage. Further details can be found…

Low blood levels of arginine are a risk factor for cardiovascular disease

Summary Arginine is the precursor for nitric oxide, a compound involved in many vascular functions such as dilation of the endothelium (inner lining of blood vessels). This review collected scientific studies to evaluate the relationship between blood levels of arginine, inflammation and cardiovascular disease. The results showed that reduced blood levels of arginine and increased…

Protective effects of the tetrapeptide Ac-SDKP against kidney damage

Summary This study investigated the effects of a natural tetrapeptide (a molecule consisting of 4 amino acids), Ac-SDKP, on kidney damage. This study was performed in mice with diabetes. The results suggested that Ac-SDKP ameliorates kidney insufficiency and kidney damage. Further details can be found in the study. References Kazuyuki Shibuya, Keizo Kanasaki, Motohide Isono, Haruhisa Sato, Mitsugu Omata, Toshiro…

Beneficial effects of vitamin C in dialysis patients

Summary This study investigated the relationship between oxidative stress (damage caused by free radicals) and chronic kidney failure in patients undergoing dialysis (process of blood purification in patients with kidney failure). Blood levels of vitamin C were measured before and after vitamin C administration. It was found that vitamin C supplementation had beneficial effects in…

Green tea extract improves kidney function

Summary This study investigated the protective effect of epigallocatechin gallate (EGCG), a green tea extract, on kidneys when treated with the drug cyclosporine (CsA). The study was carried out with rodents. The authors found that EGCG treatment significantly protected kidney function. Furthermore, the plant compound was effective against CsA-induced oxidative stress (imbalance between the production…

Zinc protects against kidney disease

Summary This study investigated the relationship between dietary zinc supplementation and the development of IgA nephropathy, a disease of the kidney. The study was conducted with 7-week-old IgA nephropathy-prone mice with low, normal or high zinc levels. The results showed that zinc deficiency was associated with kidney disease progression. Moreover, zinc supplementation was found to…

Micronutrients protect against kidney damage

Summary This study was carried out to investigate whether a micronutrient mixture, containing lysine, proline, vitamin C, N-acetylcysteine, green tea extract and other micronutrients, had protective effects on paracetamol-induced damage to the liver and kidneys. Four groups of mice (A, B, C, and D) were investigated. Groups A and C were fed a regular diet…

Vitamin B12 malabsorption in patients with HIV

Summary This study evaluated blood levels of vitamin B12 in patients with acquired immunodeficiency syndrome (AIDS). 11 patients with AIDS and vitamin B12 malabsorption (poor intestinal absorption of vitamin B12) were investigated. In addition, 15% of 121 patients with AIDS and 7% of 27 patients without AIDS who were HIV-positive had low vitamin B12 levels.…

Vitamin A supplementation improves health condition of HIV-infected children

Summary This study evaluated the effects of vitamin A supplementation in children born to human immunodeficiency virus (HIV)-infected women. 118 offspring of HIV-infected women were included in this investigation. The results showed that vitamin A supplementation for children of HIV-infected women appeared to be beneficial, particularly for diarrhea among HIV-infected children. More details can be…

Green tea compounds inhibit HIV

Summary This study determined the effects of epigallocatechin-3-gallate (EGCG), one of the components of green tea, on human immunodeficiency virus (HIV) infection. HIV-infected cells were treated with EGCG. The results showed that EGCG strongly inhibited the replication of the virus. More details can be found in the study. References Gianfranco Fassina, Anna Buffa, Roberto Benelli, Oliviero E Varnier, Douglas…