Summary The study determined the effect of breast-feeding on osteoporosis, especially in people with low calcium intakes and vitamin D deficiencies. Data from 1231 postmenopausal women were analysed, and it was found an increase in the risk of osteoporosis was found in women with prolonged breast-feeding histories. The authors concluded that calcium and vitamin D…
Summary This study evaluated the effect of vitamin C on bone density. Dietary information of a total of 1,196 postmenopausal women aged 50 years and older were assessed using a questionnaire. The results showed that dietary vitamin C intake was positively associated with bone density in postmenopausal women, and inadequate vitamin C intake could increase…
Summary This study examined the effect of vitamin C administration on oxidative stress (imbalance between the production of free radicals production and the body´s antioxidant defences) in pregnant women with diabetes (gestational diabetes). 200 women with gestational diabetes were given vitamin C or no supplementation. The results showed that vitamin C reverses the oxidative stresses…
Summary This review provides an overview of the currently available evidences on the effect of vitamin K supplementation in the management of diabetes. The results reported the beneficial role of vitamin K supplementation in preventing insulin resistance (the diminished ability of the body to respond to the action of insulin in decreasing blood sugars) and…
Summary This publication presents data on blood levels of vitamin D in patients with diabetes and in people without the disease. The results indicated that both type 1 and type 2 diabetic patients have lower levels of vitamin D when compared with non-diabetic people. More details can be found in the study. References Shen L,…
Summary This study investigated whether vitamin C is able to protect the heart against myocardial infarction (heart attack). The experiments were performed with rats that received vitamin C once a day for seven days. The results suggested that vitamin C administration was able to prevent heart attacks. Further details can be found in the study.…
Summary This study investigated the effect of vitamin C administration in smokers. Blood flow was analyzed in 11 smokers and 8 non-smokers, before and after vitamin C administration. The results showed that vitamin C restored impaired blood flow in smokers. Further details can be found in the study. References P A Kaufmann, T Gnecchi-Ruscone, M di Terlizzi, K…
Summary This study investigated the effect of vitamin C on the development of hypercholesterolemia (high blood levels of cholesterol) induced atherosclerosis. The experiments were performed with rabbits, and they showed that a high dose of vitamin C was effective in reducing atherosclerosis. The results suggest that vitamin C can prevent hypercholesterolemia induced atherosclerosis. Further details…
Summary Reperfusion is a treatment which aims to restore the blood flow to body´s tissues which are blood flow deficient, but it can damage organs and tissues by increasing oxidative stress (imbalance between the production of free radicals and the ability of the body to counteract their harmful effects). The present study investigated the effect…
Summary This study evaluated the relationship between vitamin C and oxidative stress (imbalance between the production of free radicals and the ability of the body to counteract their harmful effects) in patients with heart disease. The effect of oxidative stress on blood flow was measured in 12 patients with heart disease, before and after the…
Summary This study examined the relationship between vitamin C intake and the risk of coronary heart disease. 85,118 women completed a questionnaire to assess the consumption of vitamin C and other nutrients and were followed up for 16 years for the development of coronary heart disease. It was found that vitamin C supplements can reduce…
Summary This study investigated the blood levels of vitamin D in diabetic patients. 100 adolescents, including 60 with diabetes and 40 without the disease, were included. The results showed that vitamin D deficiency was associated with poor control of blood sugar levels in adolescents with diabetes. The authors concluded that vitamin D deficiency should be…
Summary This study determined the effect of vitamin C infusions on the function of the endothelium (inner lining of blood vessels) in diabetic patients. 8 adolescents with diabetes were included in the study. The results showed that vitamin C was effective against the endothelial dysfunction in adolescents with diabetes. More details can be found in…
Summary This study assessed the effect of vitamin D in patients with painful diabetic neuropathy (nerve damage). Vitamin D was administered to 143 patients with diabetes and neuropathy. The results showed that treatment with vitamin D is associated with a significant decrease in the symptoms of painful diabetic neuropathy. More details can be found in…
Summary Metalloproteinases (MMPs) are substances produced by malignant cells to digest the surrounding tissues, induce metastasis and spread through the body. This study examined the effect of various compounds on MMPs. The experiments, executed with human lung cancer cells, indicated that a nutrient mixture (NM) and the green tea-derived compound epigallocatechin gallate (EGCG) inhibited the…
Summary This study evaluated the effect of coenzyme Q10 in children with leukemia or lymphoma and treated with anthracyclines (drugs used in chemotherapy). Children were divided in two groups: group I, consisting of 10 patients with coenzyme Q10 therapy; group II, consisting of 10 patients without coenzyme Q10 therapy. The results showed a protective effect…
Summary This study evaluated the effects of vitamin C (ascorbic acid) against leukemia. The experiments showed that vitamin C reduced the growth of leukemia cells and it was concluded that vitamin C is effective against leukemia. Further details can be found in the study. References Steve Harakeh, Mona Diab-Assaf, Jihane C Khalife, Khalil A Abu-el-Ardat, Elias Baydoun, Aleksandra Niedzwiecki, Marwan E…
Summary This study evaluated the effects of a nutrient mixture containing ascorbic acid, lysine, proline and green tea on leukemia. The experiments were executed with human cells. The results showed that this special nutrient mixture reduced inflammation and inhibited the growth of leukemia cells. More details can be found in the study. References Roomi M.W.,…
Summary This study analyzed the effect of maternal prenatal vitamin supplementation with folic acid and other vitamins on childhood leukemia. Data on prenatal use of folic acid and vitamins were obtained from 12 studies, including more than 7,000 children with leukemia and 11,635 without leukemia. The results suggested that maternal prenatal use of vitamins and…
Summary This study evaluated the effect of the amino acid lysine against leukemia. Various analyses were performed, including those of cells. It was found that lysine was able to induce the death of malignant cells and decrease metalloproteinases (MMPs). MMPs are substances produced by malignant cells to digest the surrounding tissues and spread through the…
Summary This study determined the effect of fish oil supplementation among children with leukemia. 51 children were allocated into 2 groups and given either fish oil supplementation or no treatment. Compared with children who did not receive any supplementation, children who consumed fish oil had significant positive effects on appetite, caloric intake, and upper arm…
Summary This study tested the effect of a nutrient mixture (lysine, proline, ascorbic acid and green tea extract) on leukemia. The experiments were performed with human cells and it was found that this special nutrient mixture inhibited the growth of leukemia cells. More details can be found in the study. References S Harakeh, M Diab-Assaf, A Niedzwiecki, J…
Summary This study evaluated the effect of curcumin on pancreatic cancer. The experiments were performed with cells and mice. It was found that curcumin inhibited the growth and induced the death of cancer cells. In addition, mice placed on a diet containing curcumin showed smaller tumors compared with those which did not receive any supplementation.…
Summary This study evaluated the effect of a nutrient mixture containing lysine, proline, arginine, ascorbic acid and green tea extract on pancreatic cancer. The experiments, performed with cells, showed that the nutrient mixture inhibited the production of matrix metalloproteinases (MMPs). MMPs are substances produced by cancer cells to digest the surrounding tissues and spread through…
Summary This study determined the association of blood and dietary vitamin C levels with the risk of stomach cancer. Data from 215 cancer patients were compared with data from 416 participants without cancer. The results showed that high blood levels of vitamin C were associated with a reduced risk of stomach cancer. Further details can…
Summary This study evaluated the relationship between vitamin C intake and bone fracture. 366 men and 592 women (mean age 75 years) were asked to complete a questionnaire on food habits. It was found that high vitamin C intake was associated with a reduced risk of fractures. These data suggested a possible protective effect of…
Summary This study evaluated the effect of magnesium in patients undergoing coronary angioplasty (a procedure used to open the clogged arteries of the heart) for heart attack. 180 patients with heart attacks underwent successful coronary intervention. They were treated either with intravenous (directly injected into a vein) magnesium or with an intravenous solution without magnesium.…
Summary Irregular heartbeat affects approximately 30% of patients undergoing heart surgery. This study evaluated the effect of vitamins on irregular heartbeat after heart surgery. The investigation included 5 studies and a total of 567 patients, of which 284 received antioxidant vitamins. The results showed that vitamins C and E significantly reduced the onset of irregular…
Summary This study investigated the nutrition status in patients admitted to rehabilitation after heart surgery. Blood samples were collected from 50 patients and analyzed. The results showed that vitamin B12 supplementation should be encouraged because of its substantial reduction during the rehabilitation period after surgery; in addition, it was found that the diet followed during…
Summary This study evaluated the blood levels of selenium in patients undergoing heart surgery. Blood selenium was measured in 40 patients before and after heart surgery. The results showed a decrease in selenium levels after the operations. The researchers concluded that low blood levels of selenium are associated with development of complications after heart surgery.…
Summary This study tested the hypothesis that the amino acid arginine dilates blood vessels in patients undergoing heart interventions. 20 patients scheduled for surgery were given either intravenous infusion of arginine or a solution without arginine over 15 minutes. The results showed that arginine reduced vasoconstriction (narrowing of the blood vessels) after heart surgery, and…
Summary This study investigated the effect of the drug rofecoxib and folic acid and on stomach cancer. The experiments, executed with rats, indicated that rofecoxib and folic acid interfered with cancer development. The researchers concluded that high blood levels of folic acid can prevent stomach cancer. Further details can be found in the study. References…
Summary This study evaluated the relationship between dietary intake of quercetin and stomach cancer. 505 patients with stomach cancer and 1116 participants without cancer were investigated. The results showed that high dietary intake of quercetin is related to a reduced risk of non-cardia gastric adenocarcinoma (cancer of the lower stomach). More details can be found…
Summary This study evaluated the relationship between nutrients intake and stomach cancer. 338 patients with stomach cancer and 679 participants without cancer were investigated. It was found that fats increase the risk of stomach cancer. Conversely, supplementation with vitamins, especially with vitamin C, exerts protective effects against stomach cancer. Further details can be found in…
Summary This research collects studies on the relationship between blood levels of vitamin D and bladder cancer. A total of 89,610 participants and 2,238 patients with bladder cancer were included. The results suggested that people with higher vitamin D levels suffer from less risk of developing bladder cancer. More details can be found in the…
Summary This study evaluated the relationship between blood levels of vitamins A and E and tumor of the uterus. Blood levels of vitamins A and E were measured in 289 women with cervical intraepithelial neoplasia (early stage of the tumor) and early invasive cervical cancer. The results showed that these patients had significantly low blood…
Summary This article collects different studies on the relationship between cruciferous vegetables consumption and the risk of kidney cancer. 10 studies were included and analyzed. The authors concluded that cruciferous vegetables consumption is related to the decreased risk of kidney cancer. More details can be found in the study. References Ben Liu, Qiqi Mao, Xiao Wang, Feng Zhou, Jindan…
Summary This article evaluated studies on the effects of vitamin A on cervical cancer (cancer of the uterus). Studies on dietary vitamin A and blood levels of vitamin A were performed on a total of 12,136 participants. The results showed that higher intakes and blood levels of vitamin A were associated with a reduced risk…
Summary This publication collects recent findings focusing on the anti-toxicity and cancer-preventive properties of selenium and their implications in conventional therapies. The researchers shed light on unintended side effects in chemotherapy and the developments of novel combinatorial chemotherapeutics with selenium compounds. It was concluded that selenium had anti-cancer and protective effects. Further details can be…
Summary This article collects studies on the relationship between carotenoids intake and the risk of esophageal cancer. 10 studies including 1,958 patients with esophageal cancer and 4,529 people without cancer were analyzed. The results suggested that higher intake of carotenoids was associated with lower risk of esophageal cancer. More details can be found in the…
Summary This study analyzed the effects of omega3 fatty acids on inflammation and immune function in patients following esophageal cancer surgery. 60 patients with esophageal cancer were divided into 2 groups (30 patients in each group): in one group, omega 3 fatty acids were added to parenteral nutrition (intravenous feeding). The results showed that omega…
Summary The goal of this study was to analyze the influence of daily vitamin consumption on the frequency of esophageal cancer. 99 patients with esophageal carcinoma were compared with 50 people without cancer. The results showed that low intake of vitamins C and E correlated significantly with the development of esophageal cancer. More details can…
Summary This study assessed the effect of calcium and fiber intake on the risk of colorectal cancer. A questionnaire was administered to 1556 patients to evaluate dietary habits. The results showed that calcium and fiber intake was associated with a reduced risk of colon cancer. Further details can be found in the study. References Aleksander…
Summary This study investigated the effect of a ginger-derived compound 6-shogaol against breast cancer. Experiments were performed using cancer cells and they showed the efficacy of 6-shogaol in inhibiting tumor growth. The researchers concluded that this ginger-derived compound raises hope for its therapeutic benefit in breast cancer treatment. Further details can be found in the…
Summary This research evaluated the effect of fruit and vegetable consumption on kidney cancer risk. 13 studies were analyzed, and they included 1,478 patients with kidney cancer (709 women and 769 men) as well as 530,469 women and 244,483 men followed for up to 7 to 20 years. Participants were asked to complete a questionnaire…
Summary This study evaluated the role of soy-derived compounds, isoflavones, in the protection of lungs during radiation therapy. The experiments were performed with mice which were treated with soy isoflavones for 3 days before and up to 4 months after radiation. It was found that soy isoflavones protected the lungs against adverse effects of radiation…
Summary Quercetin is a natural antitumor substance whose derived compounds, quercetin glucuronides, can be found in the blood after ingestion of dietary supplements containing quercetin. This study investigated the effects of quercetin glucuronides in human lung cancer cells. The experiments demonstrated that quercetin glucuronides inhibit the growth and induce the death of cancer cells. More…
Summary This study investigated the effect of fish oil-derived compounds (PUFA) in patients with lung cancer. 33 patients with advanced inoperable lung cancer and undergoing chemotherapy were given either four capsules/day containing PUFA or no supplementation. It was found that fish oil-derived compounds reduced inflammation and oxidative stress. The decrease of the oxidative stress implicates…
Summary This study investigated the effect of dietary supplementation with a nutrient mixture containing lysine, proline, arginine, ascorbic acid, green tea extract, N-acetyl cysteine, selenium, copper and manganese on the development of lung tumors. Lung tumors were induced in mice which were fed either a regular diet or the same diet supplemented with a nutrient…
Summary Isoflavonoids are naturally occurring compounds and this study investigated their impact on brain tumor. The experiments were performed with cells and rats. The results revealed that dietary isoflavonoids were effective against brain tumor. Further details can be found in the study. References Tina Sehm, Zheng Fan, Ruth Weiss, Marc Schwarz, Tobias Engelhorn, Nirjhar Hore, Arnd Doerfler, Michael Buchfelder, Iiker Y Eyüpoglu, Nic E…