Vitamin D supplementation prevents acute respiratory tract infections

Summary This study is an overview of several studies on the preventive effects of vitamin D supplementation on acute respiratory tract infections. 25 eligible studies were identified based on individual participant data. These studies showed a reduced risk of acute respiratory tract infections and a preventive and protective effect in all participants after daily or…

B vitamins improve risk factors for cardiovascular disease

Summary In this study from China, subjects with stable coronary heart disease were evaluated for a positive change in their inflammation levels and blood lipids following vitamin B supplementation. After 12 weeks, concentrations of triglycerides, total cholesterol, and HDL levels were significantly improved. A change in homocysteine blood levels, considered a risk factor for numerous…

Coenzyme Q10 lowers cholesterol levels in patients with coronary heart disease

Summary A meta-analysis examined eight studies that included 267 participants in intervention groups and 259 subjects in placebo groups. The analysis results showed that taking coenzyme Q10 significantly lowered total cholesterol levels and increased HDL (“good cholesterol”) cholesterol levels in participants with coronary heart disease. Please see the study for more information. References Mohammad Vahid…

Combination of vitamin C, thiamine, and hydrocortisone beneficial for the treatment of sepsis and septic shock after cardiac surgery

Summary A combination of vitamin C, thiamine (vitamin B1), and hydrocortisone was investigated in 24 patients with septic shock after cardiac surgery. The participants were divided into two groups: group 1 received a placebo, and group 2 received a combination of the mentioned micronutrients. After 4 days, the required vasopressor dose (medication that tends to…

Combination of vitamin C, thiamine, and hydrocortisone beneficial for patients with severe pneumonia

Summary In this study, the effects of a combination of vitamin C, thiamine (vitamin B1), and hydrocortisone were investigated in a treatment group of 53 patients with severe pneumonia. These patients were compared to a control group of 46 patients who did not receive this micronutrient combination. The results showed that the mortality rate decreased…

High-dose vitamin C infusions have protective effect in Covid-19 patients

Summary This study investigated the effect of high-dose intravenous vitamin C supplementation in patients receiving intensive care treatment for Covid-19. 54 critically ill patients were involved in this study, including 26 patients who received the vitamin C infusion and 28 patients who received a placebo infusion. According to this study, vitamin C supplementation is an…

High-dose zinc infusions improve zinc levels in Covid-19 patients

Summary This study investigated the effect of high-dose zinc infusions on Covid-19 patients. 33 hospitalized adults participated in this study, including 15 patients who received a high-dose zinc infusion and 18 patients who received a placebo. Participants with zinc infusion showed an improved zinc level after the administration period, without adverse side effects. More details…

High-dose vitamin D therapy associated with reduced risk of mortality in Covid-19 patients

Summary 986 hospitalized patients with Covid-19 were involved in this study, including 151 patients (16%) who received vitamin D therapy. This study showed that supplementation of vitamin D reduced the risk of mortality in Covid-19 patients. More details can be found in the study. References Stephanie F Ling, Eleanor Broad, Rebecca Murphy, Joseph M Pappachan,…

High dose vitamin D supplementation affects inflammatory factors in COVID-19 patients

Summary This study investigated the effects of vitamin D on inflammatory factors in COVID-19 patients. One group of patients received vitamin D daily; the other group only received the standard treatment. The results showed that vitamin D supplementation has a beneficial effect on COVID-19 by reducing inflammatory factors. No side effects were observed. More details…

Green tea extract can reduce total and LDL cholesterol

Summary A double-blind, placebo-controlled study conducted by the University of Nashville investigated the relationship between a dietary supplement containing green tea extract and its effect on cholesterol levels. 240 men and women over 18 years of age with low to moderate increases in blood cholesterol (hypercholesterolemia) were examined over a period of 3 months. Study…

Catechin supplementation associated with significant reduction in LDL cholesterol levels

Summary In another large randomized, placebo-controlled clinical trial, which involved several American universities, the influence of green tea extracts (catechins) was investigated. The study participants were all postmenopausal women, with 936 of them completing the one-year trial. Compared to the control group, catechin supplementation was associated with a significant reduction in total and LDL cholesterol…

Vitamin B supplementation improves risk factors of fat metabolism

Summary A randomized, double-blind, placebo-controlled trial investigated the effect of two B vitamins (folic acid and vitamin B6) on the metabolism of patients with coronary heart disease. After three months of vitamin B supplementation, the three most important risk factors of fat metabolism showed a significant improvement. Blood levels of triglycerides and total cholesterol were…

Increased vitamin C blood levels associated with reduction in LDL cholesterol and increase in HDL cholesterol

Summary As early as 1992, the USDA Human Nutrition Research Center at Tufts University in Boston published a randomized field study involving several hundreds of participants of all age groups. The results of the study showed that increased vitamin C blood levels were associated with a reduction in LDL cholesterol (“bad cholesterol”) and an increase…

Multivitamins can reduce risk of heart attacks

Summary In a clinical study in Stockholm, the association between the use of multivitamin supplements and the occurrence of heart attacks was investigated in almost 3,000 study participants. Participants taking multivitamins had a significantly reduced risk of heart attacks. Further details can be found in the study. References Mary L Fantacone, Malcolm B Lowry, Sandra L Uesugi…

Green tea associated with significant reduction in cardiovascular mortality

Summary A clinical study among more than 40,000 Japanese people, investigated the association between the intake of green tea, which is rich in natural polyphenols, and the occurrence of cardiovascular disease and cancer. The consumption of large quantities of green tea was associated with a significant reduction in cardiovascular mortality, including a clear reduction in…

Low vitamin D levels associated with significantly increased risk of cardiovascular disease

Summary A clinical study conducted at the University of Kansas investigated the associations between vitamin D blood levels, vitamin D supplementation and the incidence of cardiovascular disease. Of 10,899 patients observed over a period of 5 years and 8 months, low vitamin D levels were associated with a significantly increased risk of cardiovascular disease and…

Micronutrient supplementation has positive effect on blood supply to coronary arteries

Summary In a double-blind, placebo-controlled clinical trial involving patients with coronary heart disease, a Norwegian team of doctors showed that micronutrient supplementation with folic acid (vitamin B9) and vitamin B12 had a positive effect on the blood supply to the coronary arteries. During the study period of two years, both basic and maximum blood flow…

Increased vitamin intake has positive effect on progression of coronary heart disease

Summary A study conducted at the University of California in Los Angeles showed that an increased vitamin intake had a positive effect on the progression of coronary heart disease. This study provided strong evidence because it was documented using coronary angiography. The researchers found an association between supplementary vitamin E intake and an angiographically demonstrated…

Coenzyme Q10 reduces inflammation in sepsis

Summary 40 patients were involved in this study. 20 patients received 100 mg coenzyme Q10 twice a day in combination with a standard sepsis therapy. The other 20 patients received only the standard sepsis therapy. This study showed decreased inflammation markers and a lower death rate in the test group if the micronutrient supplementation was…

After an acute ischemic stroke, patients can benefit from antioxidant supplementation

Summary Patients during an ischemic stroke are at risk for acute brain damage and they are also at risk for further tissue damage after the stroke. Researchers from the University of Sheffield (UK) therefore studied the effects of supplementary antioxidants with or without B-group vitamins on damage during the critical period after the stroke. Ninety-six…

Magnesium improves exercise tolerance in patients with coronary artery disease

Summary Researchers of the university of Vienna (Austria) tested the effects of magnesium intake on the exercise dependent heart rate of 53 male patients with coronary artery disease (CAD). They found that, compared to a placebo, 15mmol of magnesium twice a day for 6 months significantly increased the intracellular magnesium levels. These results support the…

Diabetes risk can be reduced by daily vitamin D intake

Summary This study by various U.S. research institutes aimed to find out whether vitamin D supplementation affects the risk of diabetes. The study included 2,158 participants with prediabetes (elevated blood sugar levels that fall below the threshold to diagnose diabetes) who were assigned to either a vitamin D group (1,074 individuals) or a placebo group…

Zinc supplementation helps malnourished children with infections of the intestines

Summary This study, conducted by a Bengali and an American research institute, investigated the effects of zinc supplementation in malnourished children with shigellosis (infection of the intestines caused by Shigella bacteria). The study was conducted in a Bengali hospital and included 56 moderately malnourished children between 12 and 59 months. The children received liquid zinc or a…

Vitamin C may reduce the duration of mechanical ventilation in critically ill patients

Summary This meta-analysis included 8 trials with 685 patients in total. Results showed that vitamin C decreased the length of mechanical ventilation on average by 14%. Vitamin C showed beneficial effects, particularly in patients with the longest ventilation (most severe diseased patients). In 5 trials, including 471 patients requiring ventilation for over 10 hours, ventilation…

Supplementation with vitamin D can improve insulin needs

Summary Diabetes is a known risk factor during pregnancy, when the disease can lead to serious complications as a result of metabolic disorder. A randomized, controlled study at Shanghai University Hospital investigated the effect of vitamin D on the progression of gestational diabetes. Supplementation with high-dose vitamin D significantly improved the insulin needs and other…

Vitamin D treatment benefits type 1 diabetes patients

Summary In another randomized and controlled clinical trial, a joint team of researchers from the University Hospitals of Frankfurt and Hanover examined the effects of vitamin D administration on diabetes progression. The results of this clinical study showed that vitamin D supplementation significantly reduced insulin demands and significantly improved long-term blood glucose levels (HbA1c). No…

Vitamin D supplement can reduce long-term diabetes score

Summary 60 patients with type 2 diabetes and low vitamin D levels were enrolled in a placebo-controlled, randomized clinical trial to investigate the effect of vitamin D supplementation on the progression of the disease. Patients who received a vitamin D supplement had a significant reduction in their long-term diabetes score (HbA1c). Blood pressure and blood…

Coenzyme Q10 supplements can reduce mortality from cardiovascular disease

Summary Another randomized double-blind study was conducted as part of an international collaboration between the universities of Copenhagen, Melbourne, Vienna, Warsaw and other hospitals. The study included 420 patients and investigated the influence of coenzyme Q10 supplementation on the progression of chronic heart failure over a period of 2 years. According to the researchers, coenzyme…

Dietary supplement can improve pumping function of the heart

Summary In a randomized clinical trial involving patients suffering from chronic heart failure, the effect of dietary supplements containing a vitamin-mineral combination was investigated. The study was carried out at the Charité Clinic in Berlin and showed that the pumping function of the heart (left ventricular ejection fraction) was significantly improved by the dietary supplement.…