Arginine supplementation can lead to highly significant reduction in blood pressure

Summary In an evaluation of 11 double-blind, placebo-controlled trials, the correlation between dietary supplementation with the natural amino acid arginine and changes in blood pressure was investigated. The analysis of these trials showed that arginine supplementation led to a highly significant reduction in both systolic and diastolic blood pressure. One particularly remarkable aspect of this…

Dietary supplement containing quercetin can reduce blood pressure

Summary In a double-blind, placebo-controlled trial with patients suffering from an early form of hypertension (pre-hypertension and stage 1 hypertension), the effect of quercetin on blood pressure was investigated. This dietary supplement led to a reduction in both systolic and diastolic blood pressure. The reduction in diastolic blood pressure was statistically significant (P < 0.01).…

Vitamin C supplementation leads to significant reduction in blood pressure

Summary An analysis of 8 clinical trials investigating the association between vitamin C supplementation and essential hypertension showed that vitamin C supplementation led to a significant reduction in blood pressure. For daily supplementation above 500 mg of vitamin C, these results were even statistically significant (P = 0.005). What is particularly remarkable about this research…

Vitamin E intake and risk of amyotrophic lateral sclerosis: a pooled analysis of data from 5 prospective cohort studies

Summary This study examined 5 earlier studies and investigated whether vitamin E intake was associated with amyotrophic lateral sclerosis (ALS). The researchers found that long-term vitamin E supplement use was associated with lower ALS rates and concluded that a possible protective effect of vitamin E in this disease deserves further consideration. Further details can be…

Vitamin D confers protection to motoneurons and is a prognostic factor of amyotrophic lateral sclerosis

Summary This study reports that a severe vitamin D deficiency in amyotrophic lateral sclerosis (ALS) patients accelerates the rate of decline by 4 times and is associated with a marked shorter life expectancy. The researchers say their findings support a neuroprotective function of vitamin D on motoneurons and propose vitamin D as a reliable prognostic…

Intakes of vitamin C and carotenoids and risk of amyotrophic lateral sclerosis: pooled results from 5 cohort studies

Summary This study investigated the risk of amyotrophic lateral sclerosis (ALS) by analyzing 5 studies involving a total of over 1.1 million participants. The researchers found that consumption of foods high in carotenoids may help prevent or delay onset of ALS. Further details can be found in the study. References Aleksandra Niedzwiecki, Mohd Waheed Roomi, Tatiana Kalinovsky…

Intake of polyunsaturated fatty acids and vitamin E reduces the risk of developing amyotrophic lateral sclerosis

Summary This study was based on a food-frequency questionnaire and assessed whether dietary intake of fatty acids, cholesterol, glutamate or antioxidants was associated with the risk of developing amyotrophic lateral sclerosis (ALS). The researchers concluded that a high intake of polyunsaturated fatty acids and vitamin E is associated with a 50-60% decreased risk of developing…

Fruit and vegetable intake and risk of amyotrophic lateral sclerosis in Japan

Summary This study investigated the relationship between dietary intake of vegetables, fruit, and antioxidants and the risk of amyotrophic lateral sclerosis (ALS). Its findings suggest that higher intake of food rich in antioxidants such as fruit and vegetables confer protection against the development of ALS. Further details can be found in the study. References Sheweita…

Effect of ultrahigh-dose methylcobalamin on compound muscle action potentials in amyotrophic lateral sclerosis: a double-blind controlled study

Summary This double-blind trial compared the effects of the methylcobalamin form of vitamin B12 on muscle function in amyotrophic lateral sclerosis (ALS) patients when given intramuscularly in ultrahigh-dose (25 mg/day) and low-dose (0.5 mg/day) for 14 days. The researchers found that ultrahigh-dose intramuscular injection of methylcobalamin may provide a clinically useful measure to improve or…

Blood levels of trace metals and amyotrophic lateral sclerosis

Summary This case-control study examined blood levels of trace metals in amyotrophic lateral sclerosis (ALS). The researchers found that selenium and zinc were inversely associated with ALS, particularly among patients with worse function, suggesting that supplementation with these nutrients may benefit such patients. Further details can be found in the study. References Arch Med Res.…

Nutrient mixture inhibits cancer progression

Summary Evidently, cancer progression, metastasis and shortened patient survival is associated with elevated levels of matrix metalloproteinase MMP-9. MMPs are substances produced by cancer cells to digest the surrounding tissues and spread through the body. Against this background, this study investigated the effect of a nutrient mixture containing lysine, proline, ascorbic acid and green tea…

Enhanced efficacy of nutrients combinations in inhibiting cancer progression

Summary This study evaluated the effect of epigallocatechin gallate (EGCG) and green tea extract independently, compared to a micronutrient mixture containing lysine, proline, ascorbic acid and green tea extract on cancer progression, indicated by matrix metalloproteinases (MMPs). MMPs are substances produced by malignant cells to digest the surrounding tissues and promote metastasis. The experiments were…

Nutrient combinations with polyphenols are effective against cancer

Summary This article focuses on the effects of different nutrient combinations with polyphenols on cancer. It included studies with experiments on human cancer cell lines. A mixture containing quercetin, curcumin, green tea, cruciferous vegetables extract (cruciferex®) and resveratrol inhibited head and neck tumor growth. Furthermore, a combination of polyphenols (quercetin and green tea extract) with…

Nutrient mixture inhibits brain tumor growth

Summary This study investigated the effect of a nutrient mixture containing ascorbic acid, lysine, proline and green tea extract on the growth of brain tumors. For the experiments, brain tumor cells were induced in mice. Afterwards they were fed a regular diet or a regular diet supplemented with the nutrient mixture for 4 weeks. The…

Vitamin E protects against cervical cancer

Summary This study evaluated whether vitamin A and E are able to decrease cervical cancer risk. The four year study included women between the ages of 16 and 40 who had cervical cancer (intraepithelial neoplasia), a precancerous condition of the cervix. It was found that vitamin E levels were significantly decreased in many cancer patients,…

Patients with tinnitus have low blood zinc levels

Summary This study investigated the effect of zinc administration in the treatment of tinnitus. Patients with tinnitus were investigated: 28 patients received zinc and 13 patients were given a placebo. It was concluded that patients with tinnitus can have low blood zinc levels and improvements in tinnitus can be achieved by zinc treatment. More details…

Positive effects of magnesium therapy in acoustic trauma

Summary Acoustic trauma is one of the major causes of hearing loss and tinnitus. This article presents some arguments that emphasize the interest of magnesium therapy in acoustic trauma. The efficacy of magnesium, administered either to prevent or to treat hearing loss, has been demonstrated in several studies in animals and in humans. More details…

Micronutrients are effective against ear ringing

Summary This study evaluated the effects of micronutrients in patients suffering from tinnitus. The patients were 44 to 85 years old and had been suffering from tinnitus for more than three consecutive months. They all took a specifically designed micronutrient supplement. The results showed that more than 75% of the patients experienced some reduction in…

Antioxidant treatment reduces tinnitus

Summary The present study evaluated the validity of antioxidant treatment in tinnitus sufferers with high oxidative stress (imbalance between free radicals production and the body´s antioxidant defenses). 31 patients with tinnitus underwent an 18-week treatment with glycerophosphorylcholine, glycerophosphorylethanolamine, beta-carotene, vitamin C and vitamin E. The results showed that oxidative stress was significantly reduced following antioxidant…

Coenzyme Q10 can decrease the tinnitus symptom

Summary This study evaluated the effects of coenzyme Q10 on tinnitus symptom. Tinnitus and blood levels of coenzyme Q10 were evaluated in 20 patients. The results showed that the supply of coenzyme Q10 in patients with a low blood levels of coenzyme Q10 can decrease the tinnitus symptom. Further details can be found in the…

Coenzyme Q10 improves hearing

Summary This study analyzed the effects of coenzyme Q10 on hearing. However, the solubility (capability of being dissolved in water) of coenzyme Q10 should be improved in order to ameliorate the efficacy in tissues and fluids. The experiments were conducted in a model of acoustic trauma in a guinea pig where the effectiveness of coenzyme…

Efficacy of magnesium in acoustic trauma

Summary This study evaluated the effects of magnesium against acoustic trauma. Tests were performed in two groups of noise-exposed guinea pigs treated either with magnesium or placebo. The results showed that permanent threshold shifts (permanent hearing loss) were significantly lower in the magnesium than in the placebo group. Further details can be found in the…

Protective properties of idebenone in noise-induced hearing loss

Summary Idebenone is an analogue of coenzyme Q10 with antioxidant properties. The present study investigated the antioxidant activity of idebenone in the rescue of acoustic trauma. Noise-induced hearing loss was provoked in guinea pigs in which idebenone was injected. The results suggested an antioxidant function of idebenone in protection from noise-induced hearing loss. More details…

Vitamin C prevents hypercholesterolemia induced atherosclerosis

Summary This study investigated the effect of vitamin C on the development of hypercholesterolemia (high blood levels of cholesterol) induced atherosclerosis. The experiments were performed with rabbits, and they showed that a high dose of vitamin C was effective in reducing atherosclerosis. The results suggest that vitamin C can prevent hypercholesterolemia induced atherosclerosis. Further details…

Effectiveness of vitamin C supplementation in patients with heart attacks and reperfusion

Summary Reperfusion is a treatment which aims to restore the blood flow to body´s tissues which are blood flow deficient, but it can damage organs and tissues by increasing oxidative stress (imbalance between the production of free radicals and the ability of the body to counteract their harmful effects). The present study investigated the effect…

Effectiveness of vitamin C infusion

Summary This study determined the effect of vitamin C infusions on the function of the endothelium (inner lining of blood vessels) in diabetic patients. 8 adolescents with diabetes were included in the study. The results showed that vitamin C was effective against the endothelial dysfunction in adolescents with diabetes. More details can be found in…

Prevalence of vitamin D deficiency in diabetic patients

Summary This publication presents data on blood levels of vitamin D in patients with diabetes and in people without the disease. The results indicated that both type 1 and type 2 diabetic patients have lower levels of vitamin D when compared with non-diabetic people. More details can be found in the study. References Role of…