Blood levels of trace metals and amyotrophic lateral sclerosis

Summary This case-control study examined blood levels of trace metals in amyotrophic lateral sclerosis (ALS). The researchers found that selenium and zinc were inversely associated with ALS, particularly among patients with worse function, suggesting that supplementation with these nutrients may benefit such patients. Further details can be found in the study. References Arch Med Res.…

Nutrient mixture inhibits cancer progression

Summary Evidently, cancer progression, metastasis and shortened patient survival is associated with elevated levels of matrix metalloproteinase MMP-9. MMPs are substances produced by cancer cells to digest the surrounding tissues and spread through the body. Against this background, this study investigated the effect of a nutrient mixture containing lysine, proline, ascorbic acid and green tea…

Enhanced efficacy of nutrients combinations in inhibiting cancer progression

Summary This study evaluated the effect of epigallocatechin gallate (EGCG) and green tea extract independently, compared to a micronutrient mixture containing lysine, proline, ascorbic acid and green tea extract on cancer progression, indicated by matrix metalloproteinases (MMPs). MMPs are substances produced by malignant cells to digest the surrounding tissues and promote metastasis. The experiments were…

Nutrient combinations with polyphenols are effective against cancer

Summary This article focuses on the effects of different nutrient combinations with polyphenols on cancer. It included studies with experiments on human cancer cell lines. A mixture containing quercetin, curcumin, green tea, cruciferous vegetables extract (cruciferex®) and resveratrol inhibited head and neck tumor growth. Furthermore, a combination of polyphenols (quercetin and green tea extract) with…

Nutrient mixture inhibits brain tumor growth

Summary This study investigated the effect of a nutrient mixture containing ascorbic acid, lysine, proline and green tea extract on the growth of brain tumors. For the experiments, brain tumor cells were induced in mice. Afterwards they were fed a regular diet or a regular diet supplemented with the nutrient mixture for 4 weeks. The…

Patients with tinnitus and noise-induced hearing loss exhibits vitamin B12 deficiency

Summary This study examined the effect of vitamin B12 deficiency on tinnitus. 57 patients with chronic tinnitus and noise-induced hearing loss, 29 patients with noise-induced hearing loss only and 27 patients demonstrating normal hearing were included. The results showed that patients with tinnitus and noise-induced hearing loss exhibited vitamin B12 deficiency in 47% of cases…

Patients with tinnitus have low blood zinc levels

Summary This study investigated the effect of zinc administration in the treatment of tinnitus. Patients with tinnitus were investigated: 28 patients received zinc and 13 patients were given a placebo. It was concluded that patients with tinnitus can have low blood zinc levels and improvements in tinnitus can be achieved by zinc treatment. More details…

Micronutrients are effective against ear ringing

Summary This study evaluated the effects of micronutrients in patients suffering from tinnitus. The patients were 44 to 85 years old and had been suffering from tinnitus for more than three consecutive months. They all took a specifically designed micronutrient supplement. The results showed that more than 75% of the patients experienced some reduction in…

Antioxidant treatment reduces tinnitus

Summary The present study evaluated the validity of antioxidant treatment in tinnitus sufferers with high oxidative stress (imbalance between free radicals production and the body´s antioxidant defenses). 31 patients with tinnitus underwent an 18-week treatment with glycerophosphorylcholine, glycerophosphorylethanolamine, beta-carotene, vitamin C and vitamin E. The results showed that oxidative stress was significantly reduced following antioxidant…

Coenzyme Q10 improves hearing

Summary This study analyzed the effects of coenzyme Q10 on hearing. However, the solubility (capability of being dissolved in water) of coenzyme Q10 should be improved in order to ameliorate the efficacy in tissues and fluids. The experiments were conducted in a model of acoustic trauma in a guinea pig where the effectiveness of coenzyme…

Efficacy of magnesium in acoustic trauma

Summary This study evaluated the effects of magnesium against acoustic trauma. Tests were performed in two groups of noise-exposed guinea pigs treated either with magnesium or placebo. The results showed that permanent threshold shifts (permanent hearing loss) were significantly lower in the magnesium than in the placebo group. Further details can be found in the…

Vitamin C prevents hypercholesterolemia induced atherosclerosis

Summary This study investigated the effect of vitamin C on the development of hypercholesterolemia (high blood levels of cholesterol) induced atherosclerosis. The experiments were performed with rabbits, and they showed that a high dose of vitamin C was effective in reducing atherosclerosis. The results suggest that vitamin C can prevent hypercholesterolemia induced atherosclerosis. Further details…

Effectiveness of vitamin C supplementation in patients with heart attacks and reperfusion

Summary Reperfusion is a treatment which aims to restore the blood flow to body´s tissues which are blood flow deficient, but it can damage organs and tissues by increasing oxidative stress (imbalance between the production of free radicals and the ability of the body to counteract their harmful effects). The present study investigated the effect…

Effectiveness of vitamin C infusion

Summary This study determined the effect of vitamin C infusions on the function of the endothelium (inner lining of blood vessels) in diabetic patients. 8 adolescents with diabetes were included in the study. The results showed that vitamin C was effective against the endothelial dysfunction in adolescents with diabetes. More details can be found in…

Vitamin C supplementation ameliorates insulin resistance and oxidative stress

Summary Diabetic patients can suffer from insulin resistance (the diminished ability of the body to respond to the action of insulin in decreasing blood sugars) and oxidative stress (imbalance between the production of free radicals production and the body´s antioxidant defenses). This study investigated the effects of vitamin C supplementation on insulin resistance and oxidative…

Alpha-lipoic acid protects from bone loss

Summary Osteoporosis is a chronic disease associated with decreased bone density. Pharmacological treatments are often limited, and a new interest in the use of naturally occurring compounds is growing. Alpha-lipoic acid is a naturally occurring compound with antioxidant properties, and current data indicate that alpha-lipoic acid protects from bone loss. More details can be found…

Maternal vitamin B12 deficiency results in growth retardation and osteoporosis in the offspring

Summary This study evaluated the effect of maternal deficiency of vitamin B12 on growth and bone mass of the offspring. The experiments, performed with an animal model, showed that vitamin B12 deficiency resulted in severe growth retardation and osteoporosis of the offspring. These results identify B12 as an essential vitamin which suggests possible therapies in…

Calcium and vitamin D prevent osteoporosis

Summary The study determined the effect of breast-feeding on osteoporosis, especially in people with low calcium intakes and vitamin D deficiencies. Data from 1231 postmenopausal women were analysed, and it was found an increase in the risk of osteoporosis was found in women with prolonged breast-feeding histories. The authors concluded that calcium and vitamin D…

Protective effects of magnesium in patients undergoing coronary angioplasty for heart attack

Summary This study evaluated the effect of magnesium in patients undergoing coronary angioplasty (a procedure used to open the clogged arteries of the heart) for heart attack. 180 patients with heart attacks underwent successful coronary intervention. They were treated either with intravenous (directly injected into a vein) magnesium or with an intravenous solution without magnesium.…

Vitamins C and E reduce irregular heartbeat after heart surgery

Summary Irregular heartbeat affects approximately 30% of patients undergoing heart surgery. This study evaluated the effect of vitamins on irregular heartbeat after heart surgery. The investigation included 5 studies and a total of 567 patients, of which 284 received antioxidant vitamins. The results showed that vitamins C and E significantly reduced the onset of irregular…

Vitamin B12 supplementation should be encouraged during the rehabilitation period after heart surgery

Summary This study investigated the nutrition status in patients admitted to rehabilitation after heart surgery. Blood samples were collected from 50 patients and analyzed. The results showed that vitamin B12 supplementation should be encouraged because of its substantial reduction during the rehabilitation period after surgery; in addition, it was found that the diet followed during…

Low blood levels of selenium are associated with complications after heart surgery

Summary This study evaluated the blood levels of selenium in patients undergoing heart surgery. Blood selenium was measured in 40 patients before and after heart surgery. The results showed a decrease in selenium levels after the operations. The researchers concluded that low blood levels of selenium are associated with development of complications after heart surgery.…

Arginine reduces vasoconstriction after heart surgery

Summary This study tested the hypothesis that the amino acid arginine dilates blood vessels in patients undergoing heart interventions. 20 patients scheduled for surgery were given either intravenous infusion of arginine or a solution without arginine over 15 minutes. The results showed that arginine reduced vasoconstriction (narrowing of the blood vessels) after heart surgery, and…