Protective effects of the tetrapeptide Ac-SDKP against kidney damage

Summary This study investigated the effects of a natural tetrapeptide (a molecule consisting of 4 amino acids), Ac-SDKP, on kidney damage. This study was performed in mice with diabetes. The results suggested that Ac-SDKP ameliorates kidney insufficiency and kidney damage. Further details can be found in the study. References Kazuyuki Shibuya, Keizo Kanasaki, Motohide Isono, Haruhisa Sato, Mitsugu Omata, Toshiro…

Lycopene reduces the risk of chronic kidney disease

Summary This study investigated the association between blood levels of the antioxidant lycopene, painkillers use and the risk of chronic kidney disease (CKD). Blood levels of antioxidants were measured in 201 patients with CKD and in 313 persons without the disease. The results showed that higher blood levels of lycopene were associated with lower risk…

Beneficial effects of vitamin C in dialysis patients

Summary This study investigated the relationship between oxidative stress (damage caused by free radicals) and chronic kidney failure in patients undergoing dialysis (process of blood purification in patients with kidney failure). Blood levels of vitamin C were measured before and after vitamin C administration. It was found that vitamin C supplementation had beneficial effects in…

Vitamin C deficiency in patients undergoing dialysis

Summary Dialysis is the process of blood purification used to treat kidney failure. Research has shown that requirements for vitamin C are increased in patients undergoing dialysis. In this study, 45 dialysis patients were tested for vitamin C insufficiency and deficiency. The results showed that vitamin C deficiency is a common finding in dialysis patients.…

Natural compound EGCG inhibits kidney stone formation

Summary This study investigated whether epigallocatechin gallate (EGCG), a green tea compound, can be protective against kidney stones. The experiments were performed with cells and rats. The results showed that EGCG inhibited kidney stone formation. Further details can be found in the study. References Byong Chang Jeong, Bong Sub Kim, Jung In Kim, Hyeon Hoe Kim   Link…

Green tea extract improves kidney function

Summary This study investigated the protective effect of epigallocatechin gallate (EGCG), a green tea extract, on kidneys when treated with the drug cyclosporine (CsA). The study was carried out with rodents. The authors found that EGCG treatment significantly protected kidney function. Furthermore, the plant compound was effective against CsA-induced oxidative stress (imbalance between the production…

Zinc protects against kidney disease

Summary This study investigated the relationship between dietary zinc supplementation and the development of IgA nephropathy, a disease of the kidney. The study was conducted with 7-week-old IgA nephropathy-prone mice with low, normal or high zinc levels. The results showed that zinc deficiency was associated with kidney disease progression. Moreover, zinc supplementation was found to…

Micronutrients protect against kidney damage

Summary This study was carried out to investigate whether a micronutrient mixture, containing lysine, proline, vitamin C, N-acetylcysteine, green tea extract and other micronutrients, had protective effects on paracetamol-induced damage to the liver and kidneys. Four groups of mice (A, B, C, and D) were investigated. Groups A and C were fed a regular diet…

Vitamin B12 malabsorption in patients with HIV

Summary This study evaluated blood levels of vitamin B12 in patients with acquired immunodeficiency syndrome (AIDS). 11 patients with AIDS and vitamin B12 malabsorption (poor intestinal absorption of vitamin B12) were investigated. In addition, 15% of 121 patients with AIDS and 7% of 27 patients without AIDS who were HIV-positive had low vitamin B12 levels.…

Vitamin B12 deficiency is common in HIV-infected patients

Summary This study assessed blood levels of vitamin B12 in human immunodeficiency virus (HIV)-infected patients. Blood levels of vitamin B12 were evaluated in 60 patients with HIV infection. The results showed that low blood levels of vitamin B12 are often found in HIV-infected patients. More details can be found in the study. References A F…

Vitamin A supplementation improves health condition of HIV-infected children

Summary This study evaluated the effects of vitamin A supplementation in children born to human immunodeficiency virus (HIV)-infected women. 118 offspring of HIV-infected women were included in this investigation. The results showed that vitamin A supplementation for children of HIV-infected women appeared to be beneficial, particularly for diarrhea among HIV-infected children. More details can be…

Vitamin B12 supplementation reverses AIDS-associated dementia

Summary Decreased blood levels of vitamin B12 often occur in patients with acquired immune deficiency syndrome (AIDS) and can contribute to nervous system disorders that are frequently attributed to the human immunodeficiency virus (HIV). This study evaluated the effect of vitamin B12 administration in a patient with AIDS and dementia. As it turned out, treatment…

Green tea compounds inhibit HIV

Summary This study determined the effects of epigallocatechin-3-gallate (EGCG), one of the components of green tea, on human immunodeficiency virus (HIV) infection. HIV-infected cells were treated with EGCG. The results showed that EGCG strongly inhibited the replication of the virus. More details can be found in the study. References Gianfranco Fassina, Anna Buffa, Roberto Benelli, Oliviero E Varnier, Douglas…

Efficacy of micronutrients against HIV

Summary This review collected scientific studies on the efficacy of micronutrients against HIV. The results were as follows: N-acetylcysteine and alpha-lipoic acid interrupted the virus activation, glutamine improved glutathione (antioxidant) levels and carnitine was effective in the (nutritional) treatment of HIV. More details can be found in the publication. References L Patrick   Link to…

N-acetylcysteine inhibits inflammation in AIDS/HIV

Summary People infected with human immunodeficiency virus (HIV) suffer from inflammation and depleted glutathione (antioxidant) levels. Inflammation itself can lead to decreased levels of glutathione. This study evaluated the ability of N-acetylcysteine to interfere with these mechanisms. The results showed that N-acetylcysteine was able to inhibit inflammation and replenish depleted glutathione levels. The researchers suggested…

Micronutrient deficiencies are associated with HIV progression

Summary This study evaluated the relationship between blood levels of nutrients and human immunodeficiency virus (HIV) progression. Proteins, zinc, iron and vitamins B1, B2, B6, B12, A, E, C and folate were measured in the blood of 108 HIV-positive men. The results showed that micronutrient deficiencies were associated with HIV progression. Further details can be…

Vitamin C inhibits human immunodeficiency virus (HIV)

Summary This study investigated the effect of vitamin C on human immunodeficiency virus (HIV). The experiments were performed with cells. The results showed that vitamin C inhibits HIV by interfering with specific enzymes that allow the virus to spread. Further details can be found in the study. References S Harakeh, A Niedzwiecki, R J Jariwalla   Link…

Arginine: a therapeutic option for treating AIDS/HIV infection

Summary Conventional drugs used to treat human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS) infection can increase the activation of the virus. This review analyzed studies on the effect of the natural amino acid arginine in fighting AIDS/HIV infection. The results showed that arginine did not increase HIV activation. The researchers concluded that these observations, together…

Vitamin C decreases the survival of HIV-infected cells

Summary This study evaluated the effects of vitamin C uptake on human immunodeficiency virus (HIV). The experiments were performed with HIV-infected and uninfected cells. The results showed that exposure to high concentrations of vitamin C decreased the growth (proliferation) and survival of the HIV-infected cells. Further details can be found in the study. References C…

Green tea extract prevents HIV infection

Summary This study evaluated the effectiveness of epigallocatechin gallate (EGCG), a green tea compound, against human immunodeficiency virus (HIV) infection. The experiments confirmed that EGCG is effective in inhibiting CD4-gp120 binding, which is the initial step of HIV entry into the cells. In the first stage of infection HIV attacks CD4 cells that normally support…

Green tea extract fights HIV infection

Summary This study evaluated the effects of epigallocatechin gallate (EGCG), a green tea compound, on human immunodeficiency virus (HIV) infection. In the first stage of infection HIV attacks CD4 cells that normally support the immune system function. The interaction between HIV and CD4 cells is made possible by the so called gp120 molecule that is…

Vitamin E and C reduce oxidative stress in HIV-infected patients

Summary Human immunodeficiency virus (HIV)-infected patients suffer from oxidative stress, which is characterized by an imbalance between the production of free radicals and the ability of the body to counteract their harmful effects. This study assessed the effect of an antioxidant vitamin supplementation on HIV-infected persons. 49 HIV-positive patients were given either vitamin E and…

Vitamins improve weight gain in HIV-infected pregnant women

Summary This study examined the effects of multivitamin and vitamin A supplements on the body weight of immunodeficiency virus (HIV)-infected pregnant women. 1075 pregnant, HIV-positive women were given multivitamins (thiamine, riboflavin, niacin, folic acid, and vitamins B-6, B-12, C, and E), vitamin A, multivitamins including vitamin A, or no supplementation on a daily basis. Weight…

Micronutrient supplementation is beneficial in HIV-infected adults

Summary This study investigated whether a specific micronutrient supplementation is effective and safe in delaying the progression of human immunodeficiency virus (HIV) infection. 878 HIV-infected adults were investigated. Over the period of 2 years, the study participants took a single supplement containing multivitamins and selenium. The supplement was found to be effective in reducing the…

Vitamin C controls HIV infection

Summary This study investigated the effects of vitamin C (ascorbic acid) and its calcium salt (Ca-ascorbate), glutathione (GSH) and N-acetyl-L-cysteine (NAC) against human immunodeficiency virus (HIV). The experiments were performed with cells. The results showed that continuous presence of vitamin C was necessary for HIV suppression. Furthermore, NAC conferred a synergistic effect when tested simultaneously…

Patients infected with HIV have low blood levels of vitamin B12

Summary This study evaluated the blood levels of vitamin B12 in HIV patients who were treated with the anti-viral drug zidovudine. 200 HIV-infected persons were investigated. The results showed that decreased vitamin B12 levels were frequently found in HIV patients treated with the anti-viral therapy. Further details can be found in the study. References O…

Beneficial effects of vitamin C in HIV/AIDS

Summary Tumor necrosis factor alpha (TNF-alpha) is a pro-inflammatory factor whose levels are elevated in patients with human immunodeficiency virus (HIV)/acquired immunodeficiency syndrome (AIDS). This study evaluated the effect of vitamin C (ascorbic acid) on virus activation following treatment with inflammatory factors. The experiments were performed with cells. The results showed that vitamin C reduced…

Vitamin A supplements reduce death rate among HIV-infected children

Summary This study determined whether vitamin A supplements reduce the number of deaths among human immunodeficiency virus (HIV)-infected and uninfected children. 687 children with pneumonia were given vitamin A or a placebo. Their blood was then tested for HIV. Among HIV-infected children, vitamin A supplements reduced deaths – regardless of their cause – by 63%.Among…

Multivitamin supplementation delays HIV progression

Summary This study examined the effects of a daily intake of micronutrient supplements containing vitamin A, multivitamins (vitamins B, C, and E) or both on progression of human immunodeficiency virus (HIV). 1078 pregnant women infected with HIV were investigated. The results showed that multivitamin supplements delayed the virus progression and the initiation of antiretroviral therapy…

Arginine supplementation is safe for HIV/AIDS patients

Summary This study evaluated the safety and efficacy of supplemental arginine in persons with human immunodeficiency virus (HIV) and acquired immunodeficiency syndrome (AIDS). 11 HIV-infected adults received either arginine or a placebo for 14 days. The results showed that short-term arginine supplementation is safe for persons with HIV/AIDS. Further details can be found in the…

Omega-3 fatty acids prevent mental decline

Summary Alzheimer’s disease is the leading cause of dementia and the most common neurodegenerative disease in the elderly. This review analyzed epidemiological, dietary intervention and supplementation studies on Alzheimer’s disease. According to the review, the studies supported the role of omega-3 fatty acids in the prevention or delay of mental decline (reduction of brain function)…

Healthy diets can protect against Alzheimer´s disease

Summary This study evaluated the relationship between diet and Alzheimer’s disease in normal individuals at risk for this disease. Data from 52 people were analyzed. The association between nutrients and brain function was assessed by means of a questionnaire. The researchers found that higher intakes of fresh fruit and vegetables, whole grains, fish and low-fat…

Omega-3 fatty acids reduce inflammation in Alzheimer’s disease

Summary Neuroinflammation, an inflammation of the nervous system, is a characteristic of a multitude of nervous system disorders. This review summarized 61 studies that tested the effect of omega-3 on neuroinflammation in various diseases, including Alzheimer’s disease. The results showed that omega-3 fatty acids have anti-inflammatory properties and can fight neuroinflammation in this brain disease.…

Micronutrient supplement improves brain function

Summary The present study examined the effect of a micronutrient combination on brain function. The supplement consisted of curcumin, piperine, epigallocatechin gallate, α-lipoic acid, N-acetylcysteine, B vitamins, vitamin C and folate and was administered for 6 months to mice affected by Alzheimer´s disease. The results of this examination revealed that the micronutrient combination improved brain…

Flavonoids are effective protective agents against Alzheimer’s disease

Summary The brains of patients with Alzheimer’s disease have an abundance of amyloid plaques, made up of protein fragments. The excessive accumulation of these proteins is believed to be a key mechanism responsible for brain cell death in Alzheimer’s disease. The present study aimed to identify flavonoids (naturally occurring compounds) that could inhibit amyloid plaques-induced…

Vitamin E inhibits Alzheimer’s progression

Summary This study determined if vitamin E, the drug memantine, or a combination of both slow the progression of Alzheimer´s disease. 613 patients affected by Alzheimer´s disease received either vitamin E, memantine, vitamin E and memantine combined, or a placebo. It was discovered that vitamin E administration led to a slower progression of the disease.…

Vitamin E protects against dementia

Summary This study analyzed the relationship between blood levels of vitamin E and dementia. Blood levels of vitamin E were investigated in 1033 participants aged 65 years and older. The results showed that higher vitamin E blood levels can provide significant protection against mental impairment and dementia in elderly people. Further details can be found…