In recent years, many studies have shown positive effects of vitamin D on health, including various benefits to inflammation and immune response, cognitive function, protection against metabolic syndrome and cardiovascular disease. Vitamin D deficiency has been closely related to the development of coronary heart disease and its mortality.Vitamin D involvement in mitigating the pathogenesis and progression of CHD may occur at different levels, such as by regulation of renin-angiotensin system to lower blood pressure, promotion of insulin secretion, decrease in insulin resistance, regulation of cell differentiation andproliferation, and anti-inflammatory and anti-atherosclerosis effects, but the specific mechanisms have not yet been fully defined


V. Ivanov, S.Ivanova, A. Niedzwiecki, M. Rath


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