Combined magnesium and zinc supplementation beneficially affects patients with coronary artery disease and diabetes

Summary This study, executed by an Iranian and a Croatian university, aimed to analyze the effects of magnesium and zinc supplements on glucose levels, oxidative stress, and inflammation in patients with coronary artery disease and type 2 diabetes. In this study, 60 patients were divided into either a group receiving a placebo or a group…

Taurine: Anti-inflammatory effects in patients with cardiovascular disease

Summary Taurine is a common substance in human tissues, which influences cell function, among others. This review, conducted by researchers from the University of Melbourne, gives an overview of the anti-inflammatory effects of taurine on cardiovascular diseases. Taurine has been shown, for instance, to prevent cardiovascular diseases, including coronary artery disease, inducing a prolonged life…

Multiple micronutrient supplementation benefits heart failure patients

Summary This review, executed by research departments from Romania and China, aimed to elucidate the role of multiple micronutrient supplementation in heart failure patients. For this review, several publications were evaluated, which investigated the efficacy of micronutrient supplementation in heart failure. These publications showed that micronutrient supplementation induces improved health outcomes in heart failure patients…

Oral magnesium supplementation attenuates early stage atherosclerosis in women with high blood pressure

Summary This study, conducted by the universities of Rio de Janeiro and Glasgow, aimed to evaluate the effects of oral magnesium supplementation on blood pressure and vascular function in women with high blood pressure. The participants were divided into a group receiving a magnesium supplement (600 mg/day) and a group receiving a placebo. In addition,…

Magnesium effective as additional treatment in patients with cardiovascular disease

Summary This review by researchers from the University of Minneapolis, USA analyzed the results from clinical trials investigating the efficacy of magnesium supplementation for the treatment of cardiovascular diseases. Low magnesium levels are commonly observed in heart failure, diabetes, high blood pressure, and cardiovascular diseases. They are also a predictor for cardiovascular diseases and related…

Taurine and heart disease

Summary This Canadian review gives an overview of the beneficial effects of taurine in cardiovascular diseases. Studies demonstrate that taurine has a protective role for cells. Additionally, literature also shows the antioxidant properties of taurine. Therefore, supplementation of taurine is necessary and should be considered to treat cardiovascular diseases. More details can be found in…

L-arginine improves heart functions and quality of life in patients with heart failure

Summary This Iranian study aimed to investigate the effect of l-arginine supplementation on various heart functions and the quality of life in 50 patients with heart failure. During 10 weeks, the patients received either a supplement containing 3 g l-arginine per day or a placebo. Heart function, blood pressure, and quality of life were assessed…

Daily vitamin D supplementation beneficially affects high blood pressure

Summary According to research, low vitamin D levels are associated with higher blood pressure. This study, executed by research departments in Switzerland and the USA, aimed to determine whether higher daily vitamin D supplementation (2000 IU or 50µg) is more effective in controlling blood pressure among older adults than vitamin D supplementation with a standard…

Grape seed extract and vitamin C reduce harmful effects during coronary artery bypass surgery

Summary This Iranian study aimed to investigate the beneficial effect of grape seed extract and vitamin C in oxidative stress and tissue damage induced during coronary artery bypass surgery. Therefore, 87 patients undergoing coronary bypass surgery were assigned to three groups of each 29 patients. The first group was a control group without treatment; the…

L-Carnitine supplementation useful in heart failure patients submitted to bypass surgery

Summary L-carnitine blood levels are reduced after coronary artery bypass surgery. Therefore, a Brazilian trial aimed to verify whether L-carnitine supplementation could be beneficial in the recovery of L-carnitine levels in heart failure patients submitted to bypass surgery. The participants were divided into a supplementation group, administered with an oral dose of 50 mg/kg L-carnitine…

Phytosterols improve cardiovascular risk factors

Summary This Canadian review aimed to examine the ability of phytosterols – naturally occurring compounds in plant-based foods – to reduce risk factors of cardiovascular diseases. Studies showed that phytosterols can improve cholesterol levels. For instance, numerous clinical trials documented that 2 g of phytosterols per day decreases LDL cholesterol by 8–10%. Generally, phytosterols were…

L-carnitine administration shows beneficial effects in patients with beta-thalassemia

Summary This Iranian study investigated the effects of L-carnitine supplementation on the heart function of patients with beta-thalassemia, an inherited blood disorder associated with anemia that may lead to various heart conditions. During this study, 60 beta-thalassemia patients were divided into two groups and were treated with either L-carnitine or a placebo for 6 months.…

Folic acid treatment decreases risk of stroke in Chinese men with high blood pressure

Summary This study, conducted by several Chinese and American research institutes, evaluated the effect of calcium levels on stroke risk and the efficacy of folic acid supplementation to prevent stroke among patients with high blood pressure (hypertension). 19644 males patients were included and divided into two groups. The patients received either a hypertension drug and…

Taurine supplementation prevents stroke-like episodes

Summary This study, conducted by several Japanese research departments, aimed to evaluate the efficacy and safety of high-dose taurine supplementation to prevent stroke-like events resulting from a genetic disorder. Therefore, 10 patients received a high-dosed taurine supplement for 52 weeks. 80% of the patients who were administered with taurine showed a reduced frequency of stroke-like…

Vitamin D protects against deep vein thrombosis

Summary A Turkish study examined whether vitamin D levels are related to deep vein thrombosis. It included 140 participants in the thrombosis group and 140 in the control group. Basic and general information about the participants (age, gender, height, weight and BMI), comorbidities and vitamin D levels were recorded and compared between the two groups.…

Vitamin D supplementation improves vascular function in patients with chronic kidney disease (1)

Summary This study, conducted by Indian, Australian, and British research institutes, examined whether vitamin D supplementation can improve vascular function and subsequently decrease the mortality of patients with chronic kidney disease. 120 non-diabetic patients with moderate to severe kidney damage and vitamin D deficiency were involved in the study. The patients received a high-dose vitamin…

Coenzyme Q10 helps prevent and treat cardiovascular diseases

Summary This review by Russian and Moldavian research institutes gives an overview of studies on the role of coenzyme Q10 in cardiovascular diseases. It shows that coenzyme Q10 supplementation can be a beneficial method to prevent and treat cardiovascular diseases, like high blood pressure, ischemic heart disease, myocardial infarction, heart failure, and heart muscle inflammation.…

Omega-3 fish oil reduces the risk of cardiovascular diseases

Summary This study by Australian researchers investigated the effects of omega-3 fish oil supplementation on cardiovascular health. 20 young and healthy adults were involved in this study. Participants were divided into either a group receiving an omega-3 supplement or a placebo product. Among others, omega-3 levels and heart rate were measured. The results showed a…

Vitamin C supplementation improves inflammation in obese adults

Summary Obesity is associated with chronic inflammation. Thus, this study investigated the anti-inflammatory capacity of vitamin C in obese patients. 64 obese participants with high blood pressure and/or diabetes and high levels of inflammatory markers were enrolled into either the experimental group (31 patients) or the control group (33 patients). The experimental group was treated…

Coronary artery disease: Omega-3 fatty acids and vitamin E show beneficial effects

Summary This Iranian study investigated the effects of a combined omega-3 and vitamin E supplementation in patients with coronary artery disease. Both substances play a critical role in regulating oxidative stress and inflammation processes. 60 male patients with coronary artery disease were involved in the study and categorized into three groups: the first group received…

High-dose vitamin D supplementation decreases occurrence of atrial fibrillation after coronary bypass surgery

Summary This Turkish study investigated the preventive effect of high-dose vitamin D supplementation on the occurrence of atrial fibrillation after coronary artery bypass surgery. 116 patients with vitamin D deficiency or insufficiency were divided into two groups: 58 patients (treatment group) received oral vitamin D 48h before the surgery. The other group, which also included…

Antioxidant consumption benefits candidates for coronary artery bypass surgery

Summary This Iranian study aimed to evaluate the potential beneficial effects of dietary antioxidants on several cardiovascular risk factors in patients waiting for coronary artery bypass surgery. In this study, 454 hospitalized patients aged between 35 and 80 years were involved. Vitamin D levels and other parameters and were measured in blood. Also, the level…

Coenzyme Q10 treatment lowers blood pressure and improves lipid and glucose levels

Summary This study by different Chinese research institutes investigated the effect of coenzyme Q10 on several risk factors for cardiovascular diseases in patients with abnormal blood lipid levels. 101 patients who did not take any lipid- or glucose-lowering drugs received coenzyme Q10 (120 mg) or a placebo daily for 24 weeks. Several parameters were measured…

Omega-3 fatty acids and antioxidant vitamins can prevent atrial fibrillation after bypass surgery

Summary A study at the University of Chile explored whether omega-3 fatty acids and specific vitamins can strengthen the antioxidant system and, in this way, reduce the incidence of postoperative atrial fibrillation. The antioxidant system is a group of enzymes and antioxidant molecules that control the formation of free radicals and reactive oxygen compounds and…

Intravenous iron supplementation improves symptoms of heart failure

Summary A multicenter, double-blind, placebo-controlled study was conducted to evaluate the benefit and safety of long-term intravenous iron administration in patients with heart failure. For this purpose, 152 heart failure patients with iron deficiency received a daily intravenous iron supplement for one year. The treatment led to long-term improvements in the patients’ functional capacity (ability…

Quercetin reduces risk of cardiovascular disease

Summary The present study investigated whether a quercetin supplement could reduce various risk factors for cardiovascular disease. For this purpose, 93 overweight or obese subjects with metabolic syndrome (simultaneous occurrence of several cardiovascular risk factors) were studied who supplemented their diet with quercetin for 6 weeks. The final results showed that dietary supplementation contributed to…

Taurine reduces strokes

Summary This study investigated the effect of high-dose taurine supplementation in patients with recurrent stroke-like episodes. For this purpose, 10 patients were observed who received either 9 g or 12 g of taurine daily for 52 weeks. The results showed that oral taurine supplementation effectively reduced the incidence of stroke. Further details can be found…

Leucine-amino acid combination can improve body functions after stroke

Summary This study aimed to analyze the effects of a leucine-enriched amino acid supplement on muscle mass, muscle strength, and physical function in stroke patients with sarcopenia. The study involved 44 elderly stroke patients who took the aforementioned supplement for eight weeks. The subjects also performed a low-intensity rehabilitation program. The result showed that the…

Dietary supplementation with vitamins, minerals, and phytonutrients reduces the risk of heart disease

Summary The study aimed to investigate the effect of a dietary supplement on the nutritional status of healthy adults and various biomarkers of heart disease. During the 8-week study period, 60 participants received a dietary supplement consisting of multivitamins, multiminerals, and phytonutrients. It was found that the subjects’ nutritional status improved, and cardiovascular biomarkers were…

Combination of vitamin C and E has vasodilatory effect in patients with coronary heart disease

Summary Coronary heart disease is a narrowing or blockage of the coronary arteries usually caused by the buildup of plaque. In this study, Turkish scientists investigated the vasodilatory effect of vitamin C (ascorbic acid) and vitamin E (α-tocopherol) – i.e., their ability to widen blood vessels – in patients with coronary heart disease. For this…

Coenzyme Q10 reduces oxidative stress and inflammation in coronary heart disease

Summary High oxidative stress and chronic inflammation may contribute to the development of coronary heart disease. Therefore, a study from Taiwan investigated the antioxidant and anti-inflammatory effects of coenzyme Q10 in patients with coronary heart disease who were taking statins. The subjects were randomly divided into two groups. One group received 300 mg of coenzyme…

Micronutrient combination can lower LDL cholesterol

Summary This clinical cross-over study from Italy investigated the lipid-lowering effect of monacolin K, L-arginine, coenzyme Q10, and ascorbic acid. The study involved 20 patients with high cholesterol levels who supplemented their diet with the micronutrients mentioned above for 8 weeks. Subsequently, total cholesterol, low-density lipoprotein cholesterol (LDL) and high-density lipoprotein cholesterol (HDL), triglycerides, fasting…