Intravenous iron supplementation improves symptoms of heart failure

Summary A multicenter, double-blind, placebo-controlled study was conducted to evaluate the benefit and safety of long-term intravenous iron administration in patients with heart failure. For this purpose, 152 heart failure patients with iron deficiency received a daily intravenous iron supplement for one year. The treatment led to long-term improvements in the patients’ functional capacity (ability…

Dietary supplementation with vitamins, minerals, and phytonutrients reduces the risk of heart disease

Summary The study aimed to investigate the effect of a dietary supplement on the nutritional status of healthy adults and various biomarkers of heart disease. During the 8-week study period, 60 participants received a dietary supplement consisting of multivitamins, multiminerals, and phytonutrients. It was found that the subjects’ nutritional status improved, and cardiovascular biomarkers were…

Coenzyme Q10 reduces oxidative stress and inflammation in coronary heart disease

Summary High oxidative stress and chronic inflammation may contribute to the development of coronary heart disease. Therefore, a study from Taiwan investigated the antioxidant and anti-inflammatory effects of coenzyme Q10 in patients with coronary heart disease who were taking statins. The subjects were randomly divided into two groups. One group received 300 mg of coenzyme…

Omega-3 fatty acids and antioxidant vitamins can prevent atrial fibrillation after bypass surgery

Summary A study at the University of Chile explored whether omega-3 fatty acids and specific vitamins can strengthen the antioxidant system and, in this way, reduce the incidence of postoperative atrial fibrillation. The antioxidant system is a group of enzymes and antioxidant molecules that control the formation of free radicals and reactive oxygen compounds and…

Taurine reduces strokes

Summary This study investigated the effect of high-dose taurine supplementation in patients with recurrent stroke-like episodes. For this purpose, 10 patients were observed who received either 9 g or 12 g of taurine daily for 52 weeks. The results showed that oral taurine supplementation effectively reduced the incidence of stroke. Further details can be found…

Leucine-amino acid combination can improve body functions after stroke

Summary This study aimed to analyze the effects of a leucine-enriched amino acid supplement on muscle mass, muscle strength, and physical function in stroke patients with sarcopenia. The study involved 44 elderly stroke patients who took the aforementioned supplement for eight weeks. The subjects also performed a low-intensity rehabilitation program. The result showed that the…

B vitamins improve risk factors for cardiovascular disease

Summary In this study from China, subjects with stable coronary heart disease were evaluated for a positive change in their inflammation levels and blood lipids following vitamin B supplementation. After 12 weeks, concentrations of triglycerides, total cholesterol, and HDL levels were significantly improved. A change in homocysteine blood levels, considered a risk factor for numerous…

Dietary intake of vitamins can reduce risk of cardiovascular disease

Summary This study investigated the effects of an increased dietary intake of vitamin C, carotenoids, and α-tocopherol (vitamin E) on the risk of cardiovascular disease. For this purpose, 69 prospective studies were analyzed that included participants who adjusted their diet according to an increased vitamin intake. The result showed that the intake of vitamin C,…

Coenzyme Q10 lowers cholesterol levels in patients with coronary heart disease

Summary A meta-analysis examined eight studies that included 267 participants in intervention groups and 259 subjects in placebo groups. The analysis results showed that taking coenzyme Q10 significantly lowered total cholesterol levels and increased HDL (“good cholesterol”) cholesterol levels in participants with coronary heart disease. Please see the study for more information. References Mohammad Vahid…

Magnesium improves exercise tolerance in patients with coronary artery disease

Summary Researchers of the university of Vienna (Austria) tested the effects of magnesium intake on the exercise dependent heart rate of 53 male patients with coronary artery disease (CAD). They found that, compared to a placebo, 15mmol of magnesium twice a day for 6 months significantly increased the intracellular magnesium levels. These results support the…

After an acute ischemic stroke, patients can benefit from antioxidant supplementation

Summary Patients during an ischemic stroke are at risk for acute brain damage and they are also at risk for further tissue damage after the stroke. Researchers from the University of Sheffield (UK) therefore studied the effects of supplementary antioxidants with or without B-group vitamins on damage during the critical period after the stroke. Ninety-six…

Dietary supplement can improve pumping function of the heart

Summary In a randomized clinical trial involving patients suffering from chronic heart failure, the effect of dietary supplements containing a vitamin-mineral combination was investigated. The study was carried out at the Charité Clinic in Berlin and showed that the pumping function of the heart (left ventricular ejection fraction) was significantly improved by the dietary supplement.…

Vitamin C supplementation leads to significant reduction in blood pressure

Summary An analysis of 8 clinical trials investigating the association between vitamin C supplementation and essential hypertension showed that vitamin C supplementation led to a significant reduction in blood pressure. For daily supplementation above 500 mg of vitamin C, these results were even statistically significant (P = 0.005). What is particularly remarkable about this research…

Coenzyme Q10 supplements can reduce mortality from cardiovascular disease

Summary Another randomized double-blind study was conducted as part of an international collaboration between the universities of Copenhagen, Melbourne, Vienna, Warsaw and other hospitals. The study included 420 patients and investigated the influence of coenzyme Q10 supplementation on the progression of chronic heart failure over a period of 2 years. According to the researchers, coenzyme…

Dietary supplement containing quercetin can reduce blood pressure

Summary In a double-blind, placebo-controlled trial with patients suffering from an early form of hypertension (pre-hypertension and stage 1 hypertension), the effect of quercetin on blood pressure was investigated. This dietary supplement led to a reduction in both systolic and diastolic blood pressure. The reduction in diastolic blood pressure was statistically significant (P < 0.01).…

Arginine supplementation can lead to highly significant reduction in blood pressure

Summary In an evaluation of 11 double-blind, placebo-controlled trials, the correlation between dietary supplementation with the natural amino acid arginine and changes in blood pressure was investigated. The analysis of these trials showed that arginine supplementation led to a highly significant reduction in both systolic and diastolic blood pressure. One particularly remarkable aspect of this…

Vitamin C prevents hypercholesterolemia induced atherosclerosis

Summary This study investigated the effect of vitamin C on the development of hypercholesterolemia (high blood levels of cholesterol) induced atherosclerosis. The experiments were performed with rabbits, and they showed that a high dose of vitamin C was effective in reducing atherosclerosis. The results suggest that vitamin C can prevent hypercholesterolemia induced atherosclerosis. Further details…

Effectiveness of vitamin C supplementation in patients with heart attacks and reperfusion

Summary Reperfusion is a treatment which aims to restore the blood flow to body´s tissues which are blood flow deficient, but it can damage organs and tissues by increasing oxidative stress (imbalance between the production of free radicals and the ability of the body to counteract their harmful effects). The present study investigated the effect…

Low blood levels of selenium are associated with complications after heart surgery

Summary This study evaluated the blood levels of selenium in patients undergoing heart surgery. Blood selenium was measured in 40 patients before and after heart surgery. The results showed a decrease in selenium levels after the operations. The researchers concluded that low blood levels of selenium are associated with development of complications after heart surgery.…

Vitamin B12 supplementation should be encouraged during the rehabilitation period after heart surgery

Summary This study investigated the nutrition status in patients admitted to rehabilitation after heart surgery. Blood samples were collected from 50 patients and analyzed. The results showed that vitamin B12 supplementation should be encouraged because of its substantial reduction during the rehabilitation period after surgery; in addition, it was found that the diet followed during…

Protective effects of magnesium in patients undergoing coronary angioplasty for heart attack

Summary This study evaluated the effect of magnesium in patients undergoing coronary angioplasty (a procedure used to open the clogged arteries of the heart) for heart attack. 180 patients with heart attacks underwent successful coronary intervention. They were treated either with intravenous (directly injected into a vein) magnesium or with an intravenous solution without magnesium.…

Lower levels of folate and vitamin B6 increase the risk of atherosclerosis

Summary High levels of the amino acid homocysteine increase the risk of atherosclerosis. This study evaluated the relationship between homocysteine, atherosclerosis and B vitamins. 750 patients with vascular disease were compared with 800 healthy people. Blood levels of homocysteine, folate, vitamin B12 and vitamin B6 were determined. The results showed that lower levels of folate…

Arginine improves circulatory problems

Summary This study investigated the effects of the amino acid arginine on peripheral vascular disease, a common circulatory problem in which narrowed arteries reduce blood flow to the limbs. 39 patients were given either arginine, a conventional drug or no treatment for 3 weeks. The results showed that arginine improved the symptoms of peripheral arterial…