L-carnitine improves cardiac function in hemodialysis patients

Summary This Japanese trial investigated the effect of L-carnitine supplementation in patients undergoing hemodialysis, a treatment to filter wastes and water from the patients’ blood. The study participants were divided into a therapy group, administered with an oral L-carnitine supplement (20 mg/kg/day) for 12 months, and a control group (no L-carnitine therapy during the test…

L-carnitine and cardiovascular disease

Summary This Chinese review summarizes the effects and working mechanism of L-carnitine in cardiovascular diseases. L-carnitine beneficially affects the energy household of the heart and reduces oxidative stress and inflammation. Additionally, carnitine has been shown to reduce high blood pressure, diabetes, and other conditions considered risk factors for the development of cardiovascular diseases. The favorable…

Coenzyme Q10 supplementation in chronic hemodialysis patients

Summary Researchers from different American research institutes investigated the safety, tolerability, and efficacy of coenzyme Q10 in chronic hemodialysis patients. To this end, 20 patients were administered various doses of coenzyme Q10. Before and after supplementation, the researchers measured several markers for oxidative stress, which is usually increased in this group of patients, and coenzyme…

Coenzyme Q10 influences markers of oxidative stress in hemodialysis patients

Summary According to a study conducted by several research departments from the University of Washington, Seattle, and the Vanderbilt University Medical Center of Nashville, USA, coenzyme Q10 beneficially affects highly prevalent oxidative stress markers in hemodialysis patients with end-stage kidney disease. This study aimed to identify a therapy that reduces oxidative stress levels and improves…

Vitamin D supplementation improves vascular function in patients with chronic kidney disease (1)

Summary This study, conducted by Indian, Australian, and British research institutes, examined whether vitamin D supplementation can improve vascular function and subsequently decrease the mortality of patients with chronic kidney disease. 120 non-diabetic patients with moderate to severe kidney damage and vitamin D deficiency were involved in the study. The patients received a high-dose vitamin…

Vitamin D supplementation improves vascular function in patients chronic kidney disease (2)

Summary This study was conducted in addition to the previously mentioned vitamin D study by Indian, Australian, and British researchers. In the present study, patients who previously were included in the placebo group received a vitamin D supplement. They received two oral doses of vitamin D at 8 weeks intervals. Subsequently, the same parameters as…

Coenzyme Q10 administration benefits patients with metabolic syndrome

Summary Researchers from three Iranian research institutes investigated the effects of coenzyme Q10 on several factors influencing metabolic syndrome. This new and common lifestyle disease includes high blood pressure, obesity, and increased glucose and cholesterol levels. This trial was performed with 60 patients, aged 40 to 85 years, with overweight or obesity, type 2 diabetes,…