Summary Taiwanese research departments analyzed the level of zinc and parameters related to free radicals and oxidative stress in type 1 diabetic patients and healthy test persons. Patients with poor controlled glucose (sugar) levels were found to have significantly lower zinc levels. Additionally, levels of oxidative stress were significantly increased in diabetes patients. A significant…
Summary This review, executed by Polish researchers, aimed to present the effect of vitamin D on immune function and review human clinical studies on the use of vitamin D as adjuvant therapy in type 1 diabetes. Many studies have demonstrated, for instance, that appropriate supplementation with vitamin D reduces the risk of autoimmune diseases, including…
Summary Vitamin D deficiency is prevalent in adolescents with type 1 diabetes and is associated with diabetes-related vascular complications in adulthood. This trial, conducted by Canadian and Israelian researchers, aimed to assess the effect of vitamin D treatment on vascular function and kidney inflammation among these patients. 31 adolescents with type 1 diabetes and low…
Summary Large fluctuations in glucose (sugar) levels could influence the risk of complications in type 1 diabetes patients. This study, executed by a Brazilian university hospital, aimed to evaluate these fluctuations and insulin needs in type 1 diabetes patients supplemented with vitamin D. 22 study participants received 4000 IU/day (100 µg) and 10000 IU/day (250…
Summary The function of specific immune cells influences type 1 diabetes. Vitamin D deficiency is highly prevalent in type 1 diabetes and can aggravate immune dysfunction. In contrast, high-dose vitamin D treatment may enhance the function of immune cells and improve metabolism in type 1 diabetes patients. In this German trial, patients received either a…
Summary In this study, researchers from Iran evaluated the impact of vitamin D supplement therapy on glucose regulation in children with type 1 diabetes. In total, 30 children with type 1 diabetes and low vitamin D levels were enrolled in the study. In addition to the standard insulin therapy for diabetics, the patients also received…
Summary Previous studies have shown a link between vitamin D deficiency and glucose metabolism disorders. This Iranian study aimed to evaluate whether vitamin D administration can manage diabetes mellitus type 1. During the study, the researchers examined the effect of vitamin D on long-term glucose (HbA1c) levels of children and adolescents with type 1 diabetes.…
Summary A team of researchers from the University of Milan, Italy, aimed to test the efficacy of an antioxidant diet and an alpha-lipoic acid supplement to improve the dysfunction of the inner surface of blood vessels (endothelium). Endothelial dysfunction is one of the major causes of vascular complications. In diabetes, it is incremented, promoting the…
Summary This study, executed by the University of Teheran, Iran, and a university in Malaysia, aimed to demonstrate that a variant of vitamin D (alfacalcidol) preserves beta cell function in children newly diagnosed with type 1 diabetes. Beta cells in the pancreas produce and release insulin in response to blood glucose levels. 61 subjects were…
Summary This trial, conducted by a Brazilian university, aimed to evaluate the effect of vitamin D3 on immune cells and the decline of beta cell function in new-onset type 1 diabetes for 18 months. 38 new-onset type 1 diabetes patients were randomly assigned to receive either oral vitamin D3 (2000 IU = 50µg) or a…
Summary Taiwanese researchers explored the status of chromium, zinc, and magnesium in patients with type 1 diabetes. All these micronutrients are involved in glucose metabolism, among others. The findings showed that the concentrations of these trace elements (especially magnesium and zinc) were lower in the blood of type 1 diabetes patients than in study participants…
Summary High glucose levels result in an overproduction of free radicals, inducing oxidative stress and impairing the function of antioxidants. This trial, conducted by a research institute in India, evaluated the effect of 3 months of antioxidant supplementation in Indian children with type 1 diabetes. 90 children were allocated to three groups: 31 healthy children…
Summary This study, conducted by the Austrian universities of Graz, Vienna, and Salzburg, investigated the suppressive effect of specific regulatory immune cells in young patients with new-onset type 1 diabetes. 30 young patients were assigned to receive vitamin D3 (70 IU/kg body weight/day) or a placebo for 12 months. The immune cells (Tregs), which are…
Summary Vitamin D deficiency is prevalent in adolescents with type 1 diabetes and is associated with diabetes-related vascular complaints in adulthood. This trial, conducted by research departments from Canada and Israel, aimed to assess the efficacy of vitamin D treatment on the function of blood vessels and indicators of kidney-related inflammation in this patient group.…
Summary High blood glucose (sugar) levels are a common problem for people with diabetes. This Iranian study aimed to evaluate changes in glucose levels following vitamin D3 supplementation in children with type 1 diabetes mellitus and vitamin D deficiency. Before the study, after three months, and at the end of the study, vitamin D levels…
Summary This study, conducted by medical universities in Rome, Italy, and London, UK, aimed to evaluate whether inositol, a vitamin-like substance, plus folic acid, may improve glucose levels and reduce insulin resistance in overweight or obese type 1 diabetes patients. Insulin resistance is when cells in muscles, fat, and liver don’t respond well to insulin…
Summary A randomized, controlled clinical trial at Cairo University Medical Clinic examined the effect of a dietary supplement containing a combination of B vitamins (B1, B6 and B12) on patients with type 1 diabetes. After only 3 months, this dietary supplement led to a significant decrease in fasting blood glucose levels, long-term blood glucose (HbA1c),…
Summary In another randomized and controlled clinical trial, a joint team of researchers from the University Hospitals of Frankfurt and Hanover examined the effects of vitamin D administration on diabetes progression. The results of this clinical study showed that vitamin D supplementation significantly reduced insulin demands and significantly improved long-term blood glucose levels (HbA1c). No…
Summary 60 patients with type 2 diabetes and low vitamin D levels were enrolled in a placebo-controlled, randomized clinical trial to investigate the effect of vitamin D supplementation on the progression of the disease. Patients who received a vitamin D supplement had a significant reduction in their long-term diabetes score (HbA1c). Blood pressure and blood…
Summary This study determined the effect of vitamin C infusions on the function of the endothelium (inner lining of blood vessels) in diabetic patients. 8 adolescents with diabetes were included in the study. The results showed that vitamin C was effective against the endothelial dysfunction in adolescents with diabetes. More details can be found in…
Summary This study investigated the blood levels of vitamin D in diabetic patients. 100 adolescents, including 60 with diabetes and 40 without the disease, were included. The results showed that vitamin D deficiency was associated with poor control of blood sugar levels in adolescents with diabetes. The authors concluded that vitamin D deficiency should be…
Summary The objective of this study was to identify whether omega-3 fatty acids protect against type 2 diabetes. To this end, the researchers examined the association between the risk of type 2 diabetes and the consumption of different types of polyunsaturated fatty acids in 43,176 Chinese men and women free of chronic disease. Fatty acids…