Natural compounds are effective against liver disease

Summary This study investigated the effects of the natural compound silybin-phospholipids and vitamin E in 40 patients. The results showed that vitamin E and silybin-phospholipids had protective and anti-inflammatory effects in patients with liver disease. More details can be found in the study. References Katia Falasca, Claudio Ucciferri, Paola Mancino, Ester Vitacolonna, Domenico De Tullio, Eligio Pizzigallo, Pio Conti, Jacopo Vecchiet  …

Liver diseases are associated with low levels of vitamin D

Summary This publication collected scientific studies on blood concentrations of vitamin D in patients with gastrointestinal and liver disorders. The researchers discovered that low blood levels of vitamin D (hypovitaminosis D) are common among patients with gastrointestinal and liver disease. More details can be found in the study. References Helen M Pappa, Elana Bern, Daniel Kamin, Richard J…

Micronutrient supplementations decrease health risks associated with hepatitis

Summary This study analyzed the effects of the standard treatment of hepatitis (pegylated interferon combined with ribavirin) on the blood levels of specific micronutrients (i.e. B vitamins and iron). 152 healthy participants and 109 patients with hepatitis C, an inflammatory disease of the liver, were investigated. The results revealed that hepatitis treatment depleted micronutrient levels…

Liver diseases reduce blood levels of vitamins

Summary This study evaluated the relationship between liver diseases and blood levels of vitamins in children. Vitamins A, D and E were investigated in young patients with hepatitis and biliary atresia, a childhood disease of the liver in which the biliary system is compromised. The results showed that children suffering from these liver diseases had…

Vitamin supplementation helps to fight liver disease

Summary This study evaluated vitamin K and vitamin D concentrations in patients with liver disorders. Data from 90 patients was analyzed. The results revealed that vitamin K and vitamin D deficiencies are common in these patients, thus indicating the need for an appropriate supplementation. Further details can be found in the study. References Leon Fisher, Elizabeth…

Glutamine and vitamin E protect against liver damage

Summary This study investigated the effects of the amino acid glutamine, either alone or combined with vitamin E, against ischemia-reperfusion of the liver, a condition that damages organs and tissues and is an important cause of liver damage. The experiments were performed with rats. The researchers discovered that both glutamine and vitamin E showed protective…

Selenium and zinc protect against oxidative stress

Summary This study evaluated the protective effect of selenium and zinc against oxidative stress (imbalance between free radicals production and the body´s antioxidant defenses). The experiments were performed with rats that received cadmium, zinc and selenium in their drinking water for a period of 35 days. The results showed that selenium and zinc together protected…

Hepatitis A reduces body defenses against oxidative stress

Summary This study evaluated the relationship between blood levels of antioxidants (beta-carotene, retinol, vitamin E and vitamin C) and hepatitis A in children. Data from 19 hepatitis A patients and 29 healthy children were analyzed. The results showed that hepatitis A patients had significantly reduced blood levels of antioxidants, which are related to oxidative stress,…

Micronutrient supplementation prevents liver injury

Summary This study investigated the role of micronutrients, such as selenium, vitamin C (ascorbic acid), beta-carotene and alpha-tocopherol (vitamin E), on liver injury. The experiments were performed with rats. The results suggested that supplementation with micronutrients can prevent the development of liver injury. Further details can be found in the study. References Tunc Catal, Sehnaz Bolkent…

Tea compounds protect against hepatitis

Summary This study examined the effects of catechins (tea compounds) against hepatitis, the inflammation of the liver. The experiments were performed with ducklings which were given either catechins or no treatment. The results showed that tea catechins had significant protective effects against hepatitis. More details can be found in the study. References J Li, L Zhou, Y…

A green tea compound prevents liver toxicity

Summary This study evaluated the effects of epigallocatechin gallate (EGCG), a compound found in the green tea, on liver damage. The experiments were performed with rats. The results showed that EGCG prevents liver damage and can be useful in treating patients with liver diseases. Further details can be found in the study. References Jun-Won Yun, Young-Kyung…

Carnitine supports liver regeneration

Summary This study evaluated the effects of carnitine on liver regeneration. The experiments were performed with rats that were given either carnitine or no treatment after hepatectomy (resection of the liver by surgical operation). The results showed that carnitine increased the regeneration of the liver. Further details can be found in the study. References O…

Antioxidants protect against cadmium toxicity

Summary Cadmium is a widely distributed toxic trace metal. When exposed to this element, it can cause severe damage to the liver. This study evaluated the effects of antioxidants against cadmium-induced liver toxicity. The experiments were performed with rats. For 8 days, the animals were given cadmium and – 1 hour prior to the treatment…

Green tea extract inhibits liver fibrosis

Summary This study evaluated the effects of epigallocatechin gallate (EGCG, a compound found in green tea) on liver fibrosis, which is the development of scar tissue in the liver in response to injury or disease. The experiments were performed with rats. The results showed that EGCG can be useful in the prevention and treatment of…

Green tea compound EGCG suppresses liver inflammation

Summary This study investigated the effects of epigallocatechin gallate (EGCG), a compound found in green tea, on hepatitis (inflammation of the liver). The study was conducted using mice with liver inflammation. Treatment with EGCG suppressed inflammation and was thereby able to protect against hepatitis. More details can be found in the study. References Y Wang, Y…

Green tea extract is effective against liver fibrosis

Summary This study examined the effects of the green tea extract epigallocatechin gallate (EGCG) on liver fibrosis (development of scar tissue in the liver). The experiments were performed using cells and rats. The results demonstrated that the administration of EGCG can be useful in the treatment and prevention of liver fibrosis. Further details can be…

Zinc deficiency is associated with liver disease

Summary The present study evaluated the relationship between blood levels of zinc and chronic liver disease in children. Data from 60 children suffering from chronic liver disease were compared with data from 30 healthy children. The results showed that children with chronic liver disease had lower levels of zinc, as compared to healthy children. The…

Glutamine enhances the antioxidant defenses

Summary This study evaluated the effects of the amino acid glutamine on oxidative stress (imbalance between free radicals production and the body´s antioxidant defenses) during ischemia-reperfusion of the liver. Ischemia-reperfusion is the restoration of blood flow to body tissues that were blood flow-deficient. Ischemia-reperfusion damages organs and tissues (e.g. increasing oxidative stress) and is often…

Low zinc concentrations are associated with cirrhosis

Summary The aim of this study was to determine zinc concentrations in the blood of children and adolescents with cirrhosis (scarring of the liver). 30 patients were investigated. The results showed that low zinc levels were common among children with cirrhosis. Therefore, the researchers pointed out that zinc supplementation should be considered for patients with…

Micronutrients protect against liver damage

Summary This study evaluated the effects of a nutrient mixture on liver injury. The nutrient mixture contained micronutrients such as lysine, proline, vitamin C, and green tea extract. For 2 weeks, mice were given either a regular diet or a diet supplemented with micronutrients. The results showed that the nutrient mixture can be useful in…

The protective effects of betaine against liver diseases

Summary The present study investigated the effects of the natural compound betaine on the development of liver diseases. The experiments were performed with mice which were administered betaine in drinking water for 2 weeks. The results suggested that betaine can be protective against liver diseases. More details can be found in the study. References Sun…

Betaine protects the liver

Summary This study evaluated the effects of the natural compound betaine on liver diseases. The experiments were performed with rats. The results showed that betaine inhibited oxidative stress (imbalance between free radicals production and the body´s antioxidant defenses), which plays an important role in the development of liver injury. Further details can be found in…

Vitamin C supplementation protects against liver disease

Summary This study evaluated the effects of vitamin C (ascorbic acid) on secondary biliary cirrhosis, a serious form of liver disease. The experiments were performed using 40 rats. The results showed that vitamin C supplementation had a protective effect on secondary biliary cirrhosis. Further details can be found in the study. References Cynthia R Matos…