Protective properties of idebenone in noise-induced hearing loss

Summary Idebenone is an analogue of coenzyme Q10 with antioxidant properties. The present study investigated the antioxidant activity of idebenone in the rescue of acoustic trauma. Noise-induced hearing loss was provoked in guinea pigs in which idebenone was injected. The results suggested an antioxidant function of idebenone in protection from noise-induced hearing loss. More details…

Efficacy of magnesium in acoustic trauma

Summary This study evaluated the effects of magnesium against acoustic trauma. Tests were performed in two groups of noise-exposed guinea pigs treated either with magnesium or placebo. The results showed that permanent threshold shifts (permanent hearing loss) were significantly lower in the magnesium than in the placebo group. Further details can be found in the…

Coenzyme Q10 improves hearing

Summary This study analyzed the effects of coenzyme Q10 on hearing. However, the solubility (capability of being dissolved in water) of coenzyme Q10 should be improved in order to ameliorate the efficacy in tissues and fluids. The experiments were conducted in a model of acoustic trauma in a guinea pig where the effectiveness of coenzyme…

Antioxidant treatment reduces tinnitus

Summary The present study evaluated the validity of antioxidant treatment in tinnitus sufferers with high oxidative stress (imbalance between free radicals production and the body´s antioxidant defenses). 31 patients with tinnitus underwent an 18-week treatment with glycerophosphorylcholine, glycerophosphorylethanolamine, beta-carotene, vitamin C and vitamin E. The results showed that oxidative stress was significantly reduced following antioxidant…

Patients with tinnitus and noise-induced hearing loss exhibits vitamin B12 deficiency

Summary This study examined the effect of vitamin B12 deficiency on tinnitus. 57 patients with chronic tinnitus and noise-induced hearing loss, 29 patients with noise-induced hearing loss only and 27 patients demonstrating normal hearing were included. The results showed that patients with tinnitus and noise-induced hearing loss exhibited vitamin B12 deficiency in 47% of cases…