Endothelial dysfunction, the impaired functioning of the lining of blood vessels, is associated with a worse prognosis in patients with chronic heart failure. Japanese scientists, therefore, aimed to investigate whether coenzyme Q10 (ubiquinol) can improve the function of heart tissue (endothelium) in patients with chronic heart failure. 14 patients received either 400 mg coenzyme Q10 per day or a placebo for 3 months. Before and after treatment, endothelial function was analyzed. The study results showed a significant improvement in the heart tissue function after supplementation with ubiquinol, compared to the results in the placebo group. This indicates that ubiquinol, or coenzyme Q10, offers a valuable therapeutic option for this group of patients. Further details can be found in the study.
Kawashima et al.