Summary
The present study examined the beneficial effects of the natural compound resveratrol on diabetic changes of blood vessel walls (diabetic vasculopathy). The study was conducted with rats suffering from (artificially induced) diabetes. In the study, the animals were treated with or without resveratrol (at 0.75 mg/kg body weight) three times a day for 4-8 weeks. In resveratrol-treated rats, several vascular conditions, i.e. vascular wall thickening and vascular permeability (the capacity of a blood vessel wall to allow for the flow of small molecules in and out of the vessel), were all alleviated. In comparison, no improvements were detected in rats without resveratrol supplementation. The findings led to the conclusion that resveratrol reduces diabetes-induced vasculopathy. More details can be found in the study.
References
Kuan-Hsing Chen, Cheng-Chieh Hung, Hsiang-Hao Hsu, Yu-Hong Jing, Chih-Wei Yang, Jan-Kan Chen