The objective of this study was to assess the clinical efficacy and safety of high doses of biotin (vitamin B7) in patients suffering from progressive multiple sclerosis (MS). 23 patients with this nervous system disease were treated with 100 to 300 mg of biotin daily for up to 3 years. The results showed significant visual improvements in some patients. Additionally, 89 % of the patients with prominent spinal cord involvement (an important cause of disability in MS patients) experienced an improvement in their condition. In conclusion, these findings suggest that high doses of biotin have a beneficial impact on progressive MS. Further details can be found in the study.
Sedel et al.