This trial, conducted by researchers from the United Kingdom, Pakistan, and Qatar, aimed to assess the effect of vitamin D supplementation on the quality of life of patients with painful diabetic neuropathy. To this end, 143 patients with symptomatic diabetic neuropathy (damage or dysfunction of nerves due to diabetes) were given a high dose of vitamin D. Questionnaires assessed the quality of life at the start of the trial (before supplementation) and every four weeks. 41.3% of patients were deficient in vitamin D. Treatment with vitamin D resulted in a significant improvement in perceived symptoms and problems related to neuropathy (for instance, emotional distress). This means that vitamin D effectively improves the quality of life in patients with painful diabetic neuropathy. More details can be found in the study.
Alam et al.