This Taiwanese study aimed to investigate the lipid-lowering effects of L-carnitine supplementation in coronary artery disease patients. During this study, 47 patients were divided into a group receiving 1000 mg/day L-carnitine orally (23 patients) and a group receiving a placebo (24 patients) for 12 weeks. L-carnitine levels and various lipids, including cholesterol, HDL, and triglycerides, were measured. Supplementation led to a significantly improved L-carnitine level, HDL status, and enhanced activity of antioxidant enzymes. Moreover, the level of triglycerides in the supplementation group decreased after 12 weeks. According to the researchers, the lipid-lowering effect may be related to the antioxidative ability of L-carnitine. More details can be found in the study.
Lee et al.