This study explored the effect of high-dose vitamin D intake on the quality of life in patients with multiple sclerosis. 94 patients with multiple sclerosis were allocated to two groups: The first group received 50000 IU (1250 µg) of vitamin D3 every five days for 3 months. The second group received a placebo. The researchers assessed the quality of life at the study’s beginning and end. After 3 months, significantly improved mental health and quality of life were observed in the supplementation group compared to patients in the placebo group. More details can be found in the study.
Ashtari et al.