Since omega-3 fatty acids and curcumin have been shown to protect nerve cells from damage and suppress inflammation, a clinical trial evaluated the ability of these micronutrients to decrease a specific inflammatory substance (TNF-α) involved in migraine development. The trial was performed for 2 months and included 74 migraine patients who were divided into 4 groups: group 1 received only omega-3 fatty acids; group 2 received only curcumin; the 3rd group received a combination of both, and the 4th group received a placebo. At the study’s start and its end, TNF-α levels were measured. It turned out that the combination of omega-3 fatty acids and curcumin had significantly reduced TNF-α levels. In addition, a significant reduction in the frequency of migraine attacks was found in the combination group, which indicates that supplementation with these natural substances could be a new promising approach to migraine management. More details can be found in the study.
Abdolahi et al.