This study evaluated the role of soy-derived compounds, isoflavones, in the protection of lungs during radiation therapy. The experiments were performed with mice which were treated with soy isoflavones for 3 days before and up to 4 months after radiation. It was found that soy isoflavones protected the lungs against adverse effects of radiation including skin injury, hair loss, inflammation, and others. These results provide evidence for a protective effect of soy against radiation therapy. Further details can be found in the study.
Gilda G Hillman, Vinita Singh-Gupta, Fulvio Lonardo, David J Hoogstra, Lisa M Abernathy, Christopher K Yunker, Shoshana E Rothstein, Joseph Rakowski, Fazlul H Sarkar, Shirish Gadgeel, Andre A Konski, Michael C Joiner