Mixture Of Natural Nutrients Reduces Collagen Matrix Contraction Driven By Aortic Smooth Muscle Cells

Summary Impaired arterial smooth muscle contractility plays a leading role in the development of systemic hypertension. Structural changes, such as occlusive atherosclerotic plaque formation, and functional changes, such as hormonal disturbances, play roles in pathophysiological mechanisms of altered arterial contractility. Accelerated gel contraction was accompanied by elevated secretion of MMPs into cell culture media. We…