This Iranian study aimed to determine whether vitamin A supplementation can improve psychiatric health in multiple sclerosis (MS) patients. 101 MS patients were enrolled in this study and allocated to a treatment or placebo group. The treatment group was administered 25000 IU (7500 µg) of vitamin A per day for 6 months, followed by 10000 IU (3000 µg) of vitamin A per day for another 6 months. Various measurements, including evaluation of fatigue and depression, were performed. The treatment group showed improvements in fatigue and depression, illustrating that vitamin A supplementation helped in the treatment process and improved the psychiatric conditions of MS patients. More details can be found in the study.
Bitarafan et al.