A randomized, double-blind, placebo-controlled trial investigated the effect of two B vitamins (folic acid and vitamin B6) on the metabolism of patients with coronary heart disease. After three months of vitamin B supplementation, the three most important risk factors of fat metabolism showed a significant improvement. Blood levels of triglycerides and total cholesterol were reduced and HDL cholesterol (“good cholesterol”) was increased (P < 0.05). The blood levels of the risk factor homocysteine and inflammation values (interleukin-1 and IL-10) were also positively influenced by this dietary supplement. Further details can be found in the study.
Randi L Edwards, Tiffany Lyon, Sheldon E Litwin, Alexander Rabovsky, J David Symons, Thunder Jalili