Decreased blood levels of vitamin B12 often occur in patients with acquired immune deficiency syndrome (AIDS) and can contribute to nervous system disorders that are frequently attributed to the human immunodeficiency virus (HIV). This study evaluated the effect of vitamin B12 administration in a patient with AIDS and dementia. As it turned out, treatment with vitamin B12 resolved the symptoms over a 2-month period. The researchers concluded that AIDS-associated dementia can be reversed by the use of vitamin B12 since this condition is characterized by the interaction between vitamin B12 deficiency and HIV. More details can be found in the study.
B C Herzlich, T D Schiano