Summary
Vitamin D deficiency is prevalent in adolescents with type 1 diabetes and is associated with diabetes-related vascular complaints in adulthood. This trial, conducted by research departments from Canada and Israel, aimed to assess the efficacy of vitamin D treatment on the function of blood vessels and indicators of kidney-related inflammation in this patient group. 31 adolescents with type 1 diabetes with suboptimal vitamin D levels were enrolled and treated for 12 to 24 weeks with vitamin D3 at doses of 1000 IU (25 µg) or 2000 IU (50 µg) daily. Tests showed a significant increase in mean vitamin D levels, a significant improvement in vascular function, and a significant reduction of inflammatory parameters following vitamin D supplementation. This means that vitamin D supplementation could help prevent vascular complications in diabetes patients at an early stage. More details can be found in the study.
References
Deda et al.