Studies suggest that vitamin D deficiency is associated with metabolic disorders such as hyperglycemia (high blood sugar) and dyslipidemia (abnormal amount of lipids in the blood), as well as increased oxidative stress, which can cause a variety of diseases. Scientists at the Medical University of Łódź (Poland) explored the effect of vitamin D supplementation on DNA damage caused by oxidative stress as well as various metabolic parameters. Ninety-two subjects with vitamin D deficiency participated in the study. Forty-eight subjects received a daily vitamin D supplement (2000 IU cholecalciferol); 44 subjects were assigned to the control group. The study showed that oxidative DNA damage was reduced, independently on type 2 diabetes presence. In addition, vitamin D reduced metabolic parameters associated with insulin resistance and improved glucose and lipid metabolism. Further details can be found in the study.
Wenclewska et al.