Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system. Anti-inflammatory drugs are among the medicines used to treat MS. In the present study, an Iranian research department evaluated the effect of high-dose vitamin D on a potent anti-inflammatory cytokine (protein), IL-10, in patients with multiple sclerosis. 94 MS patients were divided into a treatment or a placebo group. Both groups received conventional therapy. Additionally, patients in the treatment group were administered 50000 IU (1250 µg) of vitamin D every 5 days for 3 months. The results showed a significant increase in IL-10 levels after taking high-dose vitamin D3, indicating that vitamin D could be helpful to reduce inflammation in MS patients. More details can be found in the study.


Ashtari et al.


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