{"id":476,"date":"2022-09-13T10:57:11","date_gmt":"2022-09-13T10:57:11","guid":{"rendered":"https:\/\/www.healthlibrary.info\/index.php\/2021\/06\/22\/effect-of-ultrahigh-dose-methylcobalamin-on-compound-muscle-action-potentials-in-amyotrophic-lateral-sclerosis-a-double-blind-controlled-study\/"},"modified":"2022-09-13T10:57:13","modified_gmt":"2022-09-13T10:57:13","slug":"effect-of-ultrahigh-dose-methylcobalamin-on-compound-muscle-action-potentials-in-amyotrophic-lateral-sclerosis-a-double-blind-controlled-study","status":"publish","type":"post","link":"https:\/\/www.healthlibrary.info\/effect-of-ultrahigh-dose-methylcobalamin-on-compound-muscle-action-potentials-in-amyotrophic-lateral-sclerosis-a-double-blind-controlled-study\/","title":{"rendered":"Effect of ultrahigh-dose methylcobalamin on compound muscle action potentials in amyotrophic lateral sclerosis: a double-blind controlled study"},"content":{"rendered":"<h3>Summary<\/h3>\n<p>This double-blind trial compared the effects of the methylcobalamin form of vitamin B12 on muscle function in amyotrophic lateral sclerosis (ALS) patients when given intramuscularly in ultrahigh-dose (25 mg\/day) and low-dose (0.5 mg\/day) for 14 days.<br \/>\nThe researchers found that ultrahigh-dose intramuscular injection of methylcobalamin may provide a clinically useful measure to improve or retard muscle wasting in ALS patients.<\/p>\n<p>Further details can be found in the study.<\/p>\n<h3>References<\/h3>\n<p>Z Shemesh,\u00a0J Attias,\u00a0M Ornan,\u00a0N Shapira,\u00a0A Shahar<\/p>\n<p>&nbsp;<\/p>\n<h4><a style=\"color: #5aadcb;\" href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/9843082\" target=\"_blank\" rel=\"noopener\">Link to article &gt;&gt;<\/a><\/h4>\n","protected":false},"excerpt":{"rendered":"<p>Summary This double-blind trial compared the effects of the methylcobalamin form of vitamin B12 on muscle function in amyotrophic lateral sclerosis (ALS) patients when given intramuscularly in ultrahigh-dose (25 mg\/day) and low-dose (0.5 mg\/day) for 14 days. The researchers found that ultrahigh-dose intramuscular injection of methylcobalamin may provide a clinically useful measure to improve or&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[269],"tags":[1786,1785,1789,1788,1783,1790,1784,1787],"_links":{"self":[{"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/posts\/476"}],"collection":[{"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/comments?post=476"}],"version-history":[{"count":1,"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/posts\/476\/revisions"}],"predecessor-version":[{"id":6230,"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/posts\/476\/revisions\/6230"}],"wp:attachment":[{"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/media?parent=476"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/categories?post=476"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/tags?post=476"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}