{"id":7206,"date":"2022-09-13T11:00:32","date_gmt":"2022-09-13T11:00:32","guid":{"rendered":"https:\/\/www.healthlibrary.info\/decrease-in-oxidative-stress-through-supplementation-of-vitamins-c-and-e-is-associated-with-a-reduction-in-blood-pressure-in-patients-with-essential-hypertension\/"},"modified":"2022-09-13T11:00:32","modified_gmt":"2022-09-13T11:00:32","slug":"decrease-in-oxidative-stress-through-supplementation-of-vitamins-c-and-e-is-associated-with-a-reduction-in-blood-pressure-in-patients-with-essential-hypertension","status":"publish","type":"post","link":"https:\/\/www.healthlibrary.info\/decrease-in-oxidative-stress-through-supplementation-of-vitamins-c-and-e-is-associated-with-a-reduction-in-blood-pressure-in-patients-with-essential-hypertension\/","title":{"rendered":"Decrease in oxidative stress through supplementation of vitamins C and E is associated with a reduction in blood pressure in patients with essential hypertension"},"content":{"rendered":"<h3>Summary<\/h3>\n<p>Plant-derived bioflavonoids have been recognized to support arterial wall structural integrity and interfere with a variety of pro-atherosclerotic stimuli. This study examined the effect of various bioflavonoids on angiotensin II-stimulated contraction by human aortic smooth muscle cells (SMC) embedded in a three-dimensional collagen matrix. Bioflavonoid inhibition of SMC contraction was found to be dependent upon structural characteristics with EGCG and quercetin showing the greatest inhibition at 97% and 120%, respectively. These results are significant since they imply that plant derived bioflavonoids have a great potential in controlling hypertension by counteracting pathophysiological effects of angiotensin.<\/p>\n<h3>References<\/h3>\n<p>Ram\u00f3n Rodrigo,\u00a0Hern\u00e1n Prat,\u00a0Walter Passalacqua,\u00a0Julia Araya,\u00a0Jean P B\u00e4chler<\/p>\n<p>&nbsp;<\/p>\n<h4><a style=\"color: #5aadcb;\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/17999638\/\" target=\"_blank\" rel=\"noopener\">Link to article &gt;&gt;<\/a><\/h4>\n","protected":false},"excerpt":{"rendered":"<p>Summary Plant-derived bioflavonoids have been recognized to support arterial wall structural integrity and interfere with a variety of pro-atherosclerotic stimuli. This study examined the effect of various bioflavonoids on angiotensin II-stimulated contraction by human aortic smooth muscle cells (SMC) embedded in a three-dimensional collagen matrix. Bioflavonoid inhibition of SMC contraction was found to be dependent&hellip;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[69],"tags":[545,1256],"_links":{"self":[{"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/posts\/7206"}],"collection":[{"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/comments?post=7206"}],"version-history":[{"count":0,"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/posts\/7206\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/media?parent=7206"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/categories?post=7206"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.healthlibrary.info\/wp-json\/wp\/v2\/tags?post=7206"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}