Clinical trials of ultra-high-dose methylcobalamin in ALS

Clinical trials of ultra-high-dose methylcobalamin in ALS

This study summarizes clinical trials of ultra-high-dose vitamin B12 in amyotrophic lateral sclerosis (ALS).
The researchers state that patients given the methylcobalamin form of vitamin B12 at a dose of 50 mg/day via a twice weekly intramuscular injection had a significantly longer survival time, or period to become respirator-bound, than those who didn’t receive it.

Further details can be found in the study.
Izumi Y, Kaji R.
Brain Nerve. 2007 Oct;59(10):1141-7.

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