Summary Metalloproteinases (MMPs) are substances produced by malignant cells to digest the surrounding tissues, induce metastasis and spread through the body. This study examined the effect of various compounds on MMPs. The experiments, executed with human lung cancer cells, indicated that a nutrient mixture (NM) and the green tea-derived compound epigallocatechin gallate (EGCG) inhibited the…
Summary This study evaluated the role of soy-derived compounds, isoflavones, in the protection of lungs during radiation therapy. The experiments were performed with mice which were treated with soy isoflavones for 3 days before and up to 4 months after radiation. It was found that soy isoflavones protected the lungs against adverse effects of radiation…
Summary This study investigated the effect of dietary supplementation with a nutrient mixture containing lysine, proline, arginine, ascorbic acid, green tea extract, N-acetyl cysteine, selenium, copper and manganese on the development of lung tumors. Lung tumors were induced in mice which were fed either a regular diet or the same diet supplemented with a nutrient…
Summary This study investigated the effect of fish oil-derived compounds (PUFA) in patients with lung cancer. 33 patients with advanced inoperable lung cancer and undergoing chemotherapy were given either four capsules/day containing PUFA or no supplementation. It was found that fish oil-derived compounds reduced inflammation and oxidative stress. The decrease of the oxidative stress implicates…
Summary Quercetin is a natural antitumor substance whose derived compounds, quercetin glucuronides, can be found in the blood after ingestion of dietary supplements containing quercetin. This study investigated the effects of quercetin glucuronides in human lung cancer cells. The experiments demonstrated that quercetin glucuronides inhibit the growth and induce the death of cancer cells. More…
Summary Dartigues JF, Dabis F, Gros N, Moise A, Bois G, Salamon R, Dilhuydy JM, Courty G. Dietary vitamin A, beta carotene and risk of epidermoid lung cancer in south-western France. Eur J Epidemiol. 1990 Sep;6(3):261-5. References J F Dartigues, F Dabis, N Gros, A Moise, G Bois, R Salamon, J M Dilhuydy, G Courty Link to article >>
Summary Knekt P, Aromaa A, Maatela J, Alfthan G, Aaran RK, Hakama M, Hakulinen T, Peto R, Teppo L. Serum selenium and subsequent risk of cancer among Finnish men and women. J Natl Cancer Inst. 1990 May 16;82(10):864-8. References P Knekt, A Aromaa, J Maatela, G Alfthan, R K Aaran, M Hakama, T Hakulinen, R Peto, L Teppo Link to article >>
Summary In this study, the relationship between calcium and other minerals with the risk of lung cancer in non-smokers was studied. For this purpose 71,267 female non-smokers, not suffering from cancer, were interviewed using a questionnaire on their dietary habits. After an average period of 11.2 years the surveyed group was re-examined. The results show…