Eicosapentaenoic acid protects against skin cancer

Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers.

In this study, omega-3 fatty acids were evaluated for their protective effect against skin cancer induced by sunlight, i.e. ultraviolet radiation. The study included 42 healthy participants who were given 4 g daily of purified omega-3 polyunsaturated fatty acids, eicosapentaenoic acid, (EPA) or monounsaturated, oleic acid, for 3 months. Supplementation of the omega-3 fatty acid eicosapentaenoic acid reduced markers of DNA damage, thus indicating a beneficial effect of EPA in the protection of skin cancer. Further details can be found in the study.
Rhodes LE, Shahbakhti H, Azurdia RM, Moison RM, Steenwinkel MJ, Homburg MI, Dean MP, McArdle F, Beijersbergen van Henegouwen GM, Epe B, Vink AA. Effect of eicosapentaenoic acid, an omega-3 polyunsaturated fatty acid, on UVR-related cancer risk in humans. An assessment of early genotoxic markers. Carcinogenesis. 2003 May;24(5):919-25.



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