Protective effects of the tetrapeptide Ac-SDKP against kidney damage

N-Acetyl-Seryl-Aspartyl-Lysyl-Proline Prevents Renal Insufficiency and Mesangial Matrix Expansion in Diabetic db/db Mice

This study investigated the effects of a natural tetrapeptide (a molecule consisting of 4 amino acids), Ac-SDKP, on kidney damage. This study was performed in mice with diabetes. The results suggested that Ac-SDKP ameliorates kidney insufficiency and kidney damage. Further details can be found in the study.
Shibuya Kazuyuki; Kanasaki Keizo; Isosno Motohide; Sato Haruhisa; Omata Mitsugu; Sugimoto Toshiro; Araki Shin-Ichi; Isshiki Keiji; Kashiwagi Atsunori; Haneda Masakazu; Koya Daisuke. N-Acetyl-Seryl-Aspartyl-Lysyl-Proline Prevents Renal Insufficiency and Mesangial Matrix Expansion in Diabetic db/db Mice. Diabetes 2005; 54(3): 838-845.



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