In an evaluation of 11 double-blind, placebo-controlled trials, the correlation between dietary supplementation with the natural amino acid arginine and changes in blood pressure was investigated. The analysis of these trials showed that arginine supplementation led to a highly significant reduction in both systolic and diastolic blood pressure. One particularly remarkable aspect of this study was that it was published in the American Heart Journal, an official body of the American Heart Association (AHA), thus gaining wide recognition, especially among cardiologists. More details can be found in the study.
Chuen Wen Tan, Liam Pock Ho, Shirin Kalimuddin ,Benjamin Pei Zhi Cherng, Yii Ean Teh, Siew Yee Thien, Hei Man Wong, Paul Jie Wen Tern, Manju Chandran ,Jason Wai Mun Chay ,Chandramouli Nagarajan, Rehena Sultana ,Jenny Guek Hong Low ,Heng Joo Ng