Homocysteine, an amino acid found in the blood, represents a risk factor for Alzheimer’s disease. This study evaluated the relationship among homocysteine, Alzheimer’s disease and levels of B vitamins in the blood. 266 participants with cognitive (mental) impairment were given either folic acid, vitamin B12 and vitamin B6 or a placebo for 2 years. The results showed that B vitamins slowed cognitive decline in patients with cognitive impairment, in particular in those with elevated homocysteine. Further details can be found in the study.
Celeste A de Jager, Abderrahim Oulhaj, Robin Jacoby, Helga Refsum, A David Smith